Comparative endopeptidase activity of Clostridium botulinum Type B Neurotoxin Complex and Recombinant Type B light Chain to explore the role of neurotoxin associated proteins in active enzyme structure

被引:0
|
作者
Riding, S [1 ]
Lindo, P [1 ]
Biegel, E [1 ]
Singh, BR [1 ]
机构
[1] Univ Massachusetts Dartmouth, Dept Chem & Biochem, N Dartmouth, MA 02747 USA
来源
FASEB JOURNAL | 2004年 / 18卷 / 08期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:C141 / C141
页数:1
相关论文
共 50 条
  • [41] PRODUCTION OF MONOCLONAL-ANTIBODIES SPECIFIC TO CLOSTRIDIUM-BOTULINUM TYPE-B NEUROTOXIN
    NOAH, CW
    POTEET, SS
    RAMOS, NC
    PEREZ, JC
    HUANG, SY
    JOURNAL OF AOAC INTERNATIONAL, 1995, 78 (02) : 381 - 385
  • [42] Role of the disulfide cleavage induced molten globule state of type A botulinum neurotoxin in its endopeptidase activity
    Cai, SW
    Singh, BR
    BIOCHEMISTRY, 2001, 40 (50) : 15327 - 15333
  • [43] Development and selection of candidate monoclonal antibodies for the detection of Clostridium botulinum neurotoxin serotype B light chain
    Trinh, Toan Van
    Nguyen, Doai Van
    Hoang, Hieu Dang
    Pham, Hung Viet
    Vu, Duong Ngoc
    Le, Phan Van
    Le, Diep Ngoc
    Vo, Cuong Viet
    Le, Lan Anh Thi
    PROTEIN EXPRESSION AND PURIFICATION, 2025, 228
  • [44] Questions about the structure of the botulinum neurotoxin B light chain in complex with a target peptide - Response to Rupp and Segelke
    Stevens, R
    Hanson, M
    NATURE STRUCTURAL BIOLOGY, 2001, 8 (08): : 664 - 664
  • [45] Substrate residues N-terminal to the cleavage site of botulinum type B neurotoxin play a role in determining the specificity of its endopeptidase activity
    Wictome, M
    Rossetto, O
    Montecucco, C
    Shone, CC
    FEBS LETTERS, 1996, 386 (2-3) : 133 - 136
  • [46] Sequence of the gene for Clostridium botulinum type B neurotoxin associated with infant botulism, expression of the C-terminal half of heavy chain and its binding activity
    Ihara, H
    Kohda, T
    Morimoto, F
    Tsukamoto, K
    Karasawa, T
    Nakamura, S
    Mukamoto, M
    Kozaki, S
    BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION, 2003, 1625 (01): : 19 - 26
  • [47] Recombination and insertion events involving the botulinum neurotoxin complex genes in Clostridium botulinum types A, B, E and F and Clostridium butyricum type E strains
    Hill, Karen K.
    Xie, Gary
    Foley, Brian T.
    Smith, Theresa J.
    Munk, Amy C.
    Bruce, David
    Smith, Leonard A.
    Brettin, Thomas S.
    Detter, John C.
    BMC BIOLOGY, 2009, 7 : 66
  • [48] QUALITATIVE CORRELATION OF THE MOUSE NEUROTOXIN AND ENZYME-LINKED IMMUNOASSAY FOR DETERMINING CLOSTRIDIUM-BOTULINUM TYPE-A AND TYPE-B TOXINS
    HUHTANEN, CN
    WHITING, RC
    MILLER, AJ
    CALL, JE
    JOURNAL OF FOOD SAFETY, 1992, 12 (02) : 119 - 127
  • [49] PROTEASE ACTIVITY OF BOTULINUM NEUROTOXIN TYPE-E AND ITS LIGHT CHAIN - CLEAVAGE OF ACTIN
    DASGUPTA, BR
    TEPP, W
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1993, 190 (02) : 470 - 474
  • [50] Crystal structure of botulinum neurotoxin type G light chain: Serotype divergence in substrate recognition
    Arndt, JW
    Yu, W
    Bi, F
    Stevens, RC
    BIOCHEMISTRY, 2005, 44 (28) : 9574 - 9580