THE INCIDENCE OF BLADDER CANCER IN IRAN: A SYSTEMATIC REVIEW AND META-ANALYSIS

Objective: There are several reports related to the incidence of bladder cancer (BC) from various geographical locations of Iran. Nevertheless, no comprehensive systematic review has conducted in this regard. Therefore, the present systematic review and meta-analysis carried out to estimate the incidence rate of BC among Iranian people. Patients and Methods: This systematic review was done based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) in October 2017. A search was performed in five international database (Medline/PubMed, Scopus, Embase, ISI/Web of Science, and Google Scholar), and four national databases (Scientific Information Database, MagIran, Barakat Knowledge Network System, and IranDoc). The incidence rate of BC was calculated using random-effect model. Results: An aggregate of 226 papers was obtained in the primary search of the databases. After further refinement of the retrieved studies, 29 studies were included. The age-standardized rate of BC was 10.92, 95% CI (9.88-11.96) and, 2.80, 95% CI (2.47-3.13) in males and females, respectively. Conclusions: The incidence of BC was lower in Iran compared to other parts of the world. However, more investigations are needed to outline the exact incidence rate and the trend of BC among Iranian population.