An update on biological therapies for pediatric allergic diseases

被引：9

作者：

Castagnoli, Riccardo ^{[1
]}

De Filippo, Maria ^{[1
]}

Votto, Martina ^{[1
]}

Marseglia, Alessia ^{[1
]}

Montagna, Lorenza ^{[1
]}

Marseglia, Gian Luigi ^{[1
]}

Licari, Amelia ^{[1
]}

机构：

[1] Univ Pavia, IRCCS San Matteo Polyclin Fdn, Dept Pediat, Pediat Clin, Viale Golgi 19, I-27100 Pavia, Italy

来源：

MINERVA PEDIATRICA | 2020年 / 72卷 / 05期

关键词：

Child; Asthma; Chronic urticaria; Dermatitis; atopic; Food hypersensitivity; SEVERE ATOPIC-DERMATITIS; DUPILUMAB TREATMENT; OMALIZUMAB; CHILDREN; ASTHMA; PLACEBO; TRIAL; LIFE; DIAGNOSIS; 1-YEAR;

D O I：

10.23736/S0026-4946.20.05993-9

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Allergic diseases represent a global health burden. Patients with allergic diseases may experience disability, reduced quality of life and productivity, emotional distress, and social restrictions. especially in the most severe cases. Current advances in unveiling the pathogenesis of allergic disorders have paved the way for the development of novel therapeutic strategies. Biological drugs have been widely studied in pediatric allergic asthma, with strong evidence of efficacy and safety. Moreover, promising results derive from studies on other conditions such as atopic dermatitis, chronic spontaneous urticaria, and food allergy. This review analyzes recent evidence on the role of biologic therapies for allergic diseases, focusing on the pediatric age.

引用

页码：364 / 371

页数：8

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