Hippospongic acid A: An unusual triterpenoic acid from a marine sponge, Hippospongia sp, which inhibits gastrulation of starfish embryos

被引:27
|
作者
Ohta, S
Uno, M
Tokumasu, M
Hiraga, Y
Ikegami, S
机构
[1] HIROSHIMA UNIV,FAC SCI,DEPT CHEM,HIGASHIHIROSHIMA 739,JAPAN
[2] HIROSHIMA UNIV,DEPT APPL BIOCHEM,HIGASHIHIROSHIMA 739,JAPAN
关键词
D O I
10.1016/0040-4039(96)01772-8
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An unusual triterpenoic acid, hippospongic acid A (1), was isolated from the marine sponge Hippospongia sp. and the structure was elucidated on the basis of its spectroscopic data. Compound 1 selectively inhibited the gastrulation of starfish embryos with a minimum inhibitory concentration of 14 mu M. Copyright (C) 1996 Elsevier Science Ltd.
引用
收藏
页码:7765 / 7766
页数:2
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