Stem cells, plasticity and cancer - uncomfortable bed fellows

被引:12
|
作者
Trounson, A [1 ]
机构
[1] Monash Univ, Monash Immunol & Stem Cell Labs, Fac Med, Clayton, Vic 3800, Australia
来源
DEVELOPMENT | 2004年 / 131卷 / 12期
关键词
D O I
10.1242/dev.01233
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Stem cell research is a vibrant and rapidly moving field of science that investigates self-renewing cells in the adult and embryo. Two debates currently exist in the stem cell field concerning the transcriptional redirection of stem cell differentiation and fate, and the reorganization of cell commitment through nuclear reprogramming caused by cell fusion and nuclear transfer. The recent Keystone Symposium in Colorado on stem cells, organised by Fiona Watt and Leonard Zon, brought together both leading and upcoming researchers in the field to explore stem cell biology and these issues.
引用
收藏
页码:2763 / 2768
页数:6
相关论文
共 50 条
  • [31] Plasticity of adult stem cells
    Turhan, AG
    TRANSFUSION CLINIQUE ET BIOLOGIQUE, 2003, 10 (03) : 103 - 108
  • [32] Stem Cells in Neurodevelopment and Plasticity
    Flora M Vaccarino
    Yosif Ganat
    Yuchun Zhang
    Wei Zheng
    Neuropsychopharmacology, 2001, 25 : 805 - 815
  • [33] Plasticity of hematopoietic stem cells
    Ogawa, Makio
    LaRue, Amanda C.
    Mehrotra, Meenal
    BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, 2015, 28 (2-3) : 73 - 80
  • [34] Plasticity of adult stem cells
    Wagers, AJ
    Weissman, IL
    CELL, 2004, 116 (05) : 639 - 648
  • [35] Epigenetics and Cancer Stem Cells: Unleashing, Hijacking, and Restricting Cellular Plasticity
    Wainwright, Elanor N.
    Scaffidi, Paola
    TRENDS IN CANCER, 2017, 3 (05): : 372 - 386
  • [36] Breast cancer stem cells and epithelial mesenchymal plasticity - Implications for chemoresistance
    Pinto, Cletus A.
    Widodo, Edwin
    Waltham, Mark
    Thompson, Erik W.
    CANCER LETTERS, 2013, 341 (01) : 56 - 62
  • [37] Tumour microenvironment and metabolic plasticity in cancer and cancer stem cells: Perspectives on metabolic and immune regulatory signatures in chemoresistant ovarian cancer stem cells
    Ahmed, Nuzhat
    Escalona, Ruth
    Leung, Dilys
    Chan, Emily
    Kannourakis, George
    SEMINARS IN CANCER BIOLOGY, 2018, 53 : 265 - 281
  • [38] The effects of phenotypic plasticity on the fixation probability of mutant cancer stem cells
    Eastman, Brydon
    Wodarz, Dominik
    Kohandel, Mohammad
    JOURNAL OF THEORETICAL BIOLOGY, 2020, 503
  • [39] Life style factors, tumor cell plasticity and cancer stem cells
    Chiodi, Ilaria
    Mondello, Chiara
    MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH, 2020, 784
  • [40] Chromatin Organization Governs Transcriptional Response and Plasticity of Cancer Stem Cells
    Wang, Yinu
    Frederick, Jane
    Medina, Karla Isabel
    Bartom, Elizabeth Thomas
    Almassalha, Luay Matthew
    Zhang, Yaqi
    Wodarcyk, Greta
    Huang, Hao
    Ye, I. Chae
    Gong, Ruyi
    Dunton, Cody Levi
    Duval, Alex
    Gonzalez, Paola Carrillo
    Pritchard, Joshua
    Carinato, John
    Topchu, Iuliia
    Li, Junzui
    Ji, Zhe
    Adli, Mazhar
    Backman, Vadim
    Matei, Daniela
    ADVANCED SCIENCE, 2025,