Muscling Up the Heart A Preadolescent Cardiomyocyte Proliferation Contributes to Heart Growth

被引：3
|
作者：
Zhang, Cheng-Hai [1 ,2 ]
Kuehn, Bernhard [3 ,4 ]
机构：
[1] Boston Childrens Hosp, Dept Cardiol, Boston, MA USA
[2] Harvard Univ, Sch Med, Dept Pediat, Boston, MA 02115 USA
[3] Harvard Stem Cell Inst, Cambridge, MA USA
[4] Harvard Univ, Dept Stem Cell & Regenerat Biol, Cambridge, MA 02138 USA
来源：
CIRCULATION RESEARCH | 2014年 / 115卷 / 08期
关键词：
MAMMALIAN CARDIOMYOCYTES; DNA-SYNTHESIS; REGENERATION; HYPERTROPHY; EXPRESSION; DIVISION; REPAIR;
D O I：
10.1161/CIRCRESAHA.114.304632
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A recent study from Naqvi et al1 in Cell shows that in mice during preadolescence, cardiomyocytes undergo a burst of proliferation that is related to a thyroid hormone surge. This study challenges the conventional model of the timing of terminal differentiation and provides a direction for further mechanistic research on cardiomyocyte proliferation and differentiation. © 2014 American Heart Association, Inc.
引用
收藏
页码：690 / 692
页数：3
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