An Alkene-Forming Cascade Reaction En Route to 2,2′-Bi(glycerol)

被引：0

作者：

Li, Xiaoxun ^{[1
]}

Livant, Peter D. ^{[1
]}

Chen, Jianjun ^{[2
]}

机构：

[1] Auburn Univ, Dept Chem & Biochem, Auburn, AL 36849 USA

[2] Southern Med Univ, Sch Pharmaceut Sci, Guangdong Prov Key Lab New Drug Screening, Guangzhou, Guangdong, Peoples R China

来源：

SYNLETT | 2018年 / 29卷 / 13期

关键词：

cascade reaction; alkenes; olefins; 2-2 '-bi(glycerol); hexaalcohol; SODIUM HYDRIDE; REDUCING AGENT; REDUCTION; OLEFINS;

D O I：

10.1055/s-0037-1610037

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of 2,3-bis(hydroxymethyl)butane-1,2,3,4-tetraol is of great interest because of its utility as a potential precursor to new dendrimers, in the preparation of unnatural lipids, and in the synthesis of open-framework coordination polymers. Synthesis of this new six-hydroxyl compound is achieved in four steps from commercially available starting materials. In this process, a new olefin-forming cascade reaction was discovered.

引用

页码：1769 / 1772

页数：4

共 50 条

[1] NEW ALKENE-FORMING REACTION - PHENANTHRENES FROM 2-(2-FORMYLPHENYL)BENZALDEHYDE BIS-TOSYLHYDRAZONE DECOMPOSITION
JUNG, ME
HAGIWARA, A
[J]. TETRAHEDRON LETTERS, 1991, 32 (26) : 3025 - 3028
[2] BASE DEPENDENCE OF TRANSITION-STATE STRUCTURE IN ALKENE-FORMING E2 REACTIONS
BACIOCCHI, E
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1979, 12 (12) : 430 - 436
[3] ELIMINATIONS FROM 1-PHENYL-2-ALKYL TOSYLATES PROMOTED BY MEONA IN MEOH - STERIC EFFECTS IN ALKENE-FORMING ELIMINATION
CHO, BR
HAN, MS
[J]. JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1993, (01): : 105 - 108
[4] FACILE SYNTHESIS OF 2,2'-BI-2-THIAZOLINES AND 2,2'-BI-2-THIAZINES
TOMALIA, DA
PAIGE, JN
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1973, 38 (22): : 3949 - 3951
[5] 2,2′-bi-2-imidazoline
Brennan, CJ
McKee, V
[J]. ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1999, 55 : 1492 - 1494
[6] Gaucheltrans equilibria of 2,2′-bi-1,3-dioxolanyl, 2,2′-dimethyl-2,2′-bi-1,3-dioxolanyl, 2,2′-bi-1,3-dithiolanyl and 2,2′-dimethyl-2,2′-bi-1,3-dithiolanyl in different media -: theory and experiment
Chen, W
Lam, YL
Wong, MW
Huang, HH
Liang, E
[J]. NEW JOURNAL OF CHEMISTRY, 2002, 26 (11) : 1686 - 1692
[7] A CONVENIENT SYNTHETIC ROUTE TO 2,2'-BIIMIDAZOLE
MATTHEWS, DP
WHITTEN, JP
MCCARTHY, JR
[J]. SYNTHESIS-STUTTGART, 1986, (04): : 336 - 337
[8] NEW SYNTHETIC ROUTE TO 2,2=-BIIMIDAZOLE
DURANTI, E
BALSAMIN.C
[J]. SYNTHESIS-STUTTGART, 1974, (11): : 815 - 816
[9] A new synthetic route to 2,2′-Bipyrroles
Jiao, Lijuan
Smith, Kevin M.
[J]. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 233
[10] COORDINATION-COMPLEXES OF 2,2'-BI-2-THIAZOLINE AND 2,2'-BI-4,5-DIHYDROTHIAZINE
NELSON, J
NELSON, SM
PERRY, WD
[J]. JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1976, (13): : 1282 - 1289

← 1 2 3 4 5 →