Critical need for pharmacologic treatment options in NAFLD: A pediatric perspective

被引：3

作者：

Friesen, Chance S. ^{[1
]}

Chan, Sherwin S. ^{[2
,3
]}

Wagner, Jonathan B. ^{[2
,3
]}

Hosey-Cojocari, Chelsea ^{[2
]}

Csanaky, Ivan L. ^{[2
,3
,4
]}

Shakhnovich, Valentina ^{[2
,3
,4
,5
]}

机构：

[1] Univ Kansas, Sch Med, Kansas City, MO USA

[2] Childrens Mercy Kansas City, 2401 Gillham Rd, Kansas City, MO 64108 USA

[3] Univ Missouri, Sch Med, Kansas City, MO 64108 USA

[4] Univ Kansas, Med Ctr, Kansas City, MO USA

[5] Ctr Childrens Hlth Lifestyles & Nutr, Kansas City, MO USA

来源：

CTS-CLINICAL AND TRANSLATIONAL SCIENCE | 2021年 / 14卷 / 03期

关键词：

D O I：

10.1111/cts.12952

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Nonalcoholic fatty liver disease (NAFLD) affects up to 70% of children with obesity and has become the number one etiology for liver transplant in the United States. Early, effective intervention is critical to prevent disease progression into adulthood. Yet, it is seldom achieved through lifestyle modification alone. Thus, children must be included in NAFLD pharmacology trials, which, to date, continue to focus primarily on adult populations. This commentary serves as a call to action.

引用

页码：781 / 783

页数：3

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