SRPK1 Inhibition, As A Way Of Targeting Pro-Angiogenic VEGF-A Production In Ocular Tumours

被引:0
|
作者
Gammons, Melissa [1 ]
Coupland, Sarah [2 ]
Dick, Andrew [3 ,4 ]
Bates, David [1 ]
机构
[1] Univ Bristol, Dept Physiol & Pharmacol, Bristol, Avon, England
[2] Univ Liverpool, Dept Mol & Clin Canc Med, Liverpool, Merseyside, England
[3] Univ Bristol, Sch Clin Sci, Bristol, Avon, England
[4] Univ Bristol, Sch Cellular & Mol Med, Bristol, Avon, England
关键词
589; melanoma; 744; tumors; 748 vascular endothelial growth factor;
D O I
暂无
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
4526
引用
收藏
页数:2
相关论文
共 45 条
  • [21] Hypoxic Preconditioning Enhances Cellular Viability and Pro-angiogenic Paracrine Activity: The Roles of VEGF-A and SDF-1a in Rat Adipose Stem Cells
    Zhao, Yang
    Zhang, Ming
    Lu, Guo-liang
    Huang, Bao-xing
    Wang, Da-wei
    Shao, Yuan
    Lu, Mu-jun
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 8
  • [22] The angiogenic potential of aggressive osteosarcoma is regulated by AUF1 through targeting VEGF-A
    Al-Khalaf, Huda H.
    INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2018, 42 : S44 - S44
  • [23] Macrophage IL-1β promotes arteriogenesis by autocrine STAT3-and NF-κB-mediated transcription of pro-angiogenic VEGF-A
    Mantsounga, Chris S.
    Lee, Cadence
    Neverson, Jade
    Sharma, Sheila
    Healy, Abigail
    Berus, Joshua M.
    Parry, Crystal
    Ceneri, Nicolle M.
    Lopez-Giraldez, Francesc
    Chun, Hyung J.
    Lu, Qing
    Sellke, Frank
    Choudhary, Gaurav
    Morrison, Alan R.
    CELL REPORTS, 2022, 38 (05):
  • [24] Nucleolin mediated pro-angiogenic role of Hydroxysafflor Yellow A in ischaemic cardiac dysfunction: Post-transcriptional regulation of VEGF-A and MMP-9
    Zou, Jiang
    Wang, Nian
    Liu, Manting
    Bai, Yongping
    Wang, Hao
    Liu, Ke
    Zhang, Huali
    Xiao, Xianzhong
    Wang, Kangkai
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2018, 22 (05) : 2692 - 2705
  • [25] Total Flavones of Abelmoschus manihot Exhibits Pro-Angiogenic Activity by Activating the VEGF-A/VEGFR2-PI3K/Akt Signaling Axis
    Zhu, Gui-Song
    Tang, Ling-Yi
    Lv, Dong-Ling
    Jiang, Meng
    AMERICAN JOURNAL OF CHINESE MEDICINE, 2018, 46 (03): : 567 - 583
  • [26] EFFECT OF VEGF INHIBITION ON LUMINAL NARROWING AND THE PRO-ANGIOGENIC PROPERTIES OF BONE MARROW-DERIVED CELLS: IMPLICATIONS FOR CARDIAC ALLOGRAFT VASCULOPATHY
    Chatur, S.
    Wong, B.
    Williams, S.
    Carthy, J.
    McManus, B.
    CANADIAN JOURNAL OF CARDIOLOGY, 2010, 26 : 116D - 116D
  • [27] Selective down-regulation of anti-angiogenic splice variants of VEGF by IGF-1 is mediated by PKC, PI-3K and SRPK1/2
    Nowak, Dawid G.
    Woolard, Jeanette
    Ladomery, Michael
    Harper, Steve J.
    Bates, Dave O.
    FASEB JOURNAL, 2008, 22
  • [28] Selective Cox-2 inhibition attenuates the perioperative increase of the tumour enhancing pro-angiogenic cytokine VEGF in human breast cancer patients
    O'Donoghue, GT
    Roche-Nagle, G
    Connolly, EM
    Harmey, J
    Bouchier-Hayes, DJ
    BRITISH JOURNAL OF SURGERY, 2004, 91 : 43 - 44
  • [29] Targeting the long noncoding RNA MALAT1 blocks the pro-angiogenic effects of osteosarcoma and suppresses tumour growth
    Zhang, Zhi-Chang
    Tang, Chun
    Dong, Yang
    Zhang, Jing
    Yuan, Ting
    Tao, Shi-Cong
    Li, Xiao-Lin
    INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2017, 13 (11): : 1398 - 1408
  • [30] μ opioid receptor stimulates a growth promoting and pro-angiogenic tumor microenvironment by transactivating VEGF receptor-2/FLK-1.
    Stephenson, EJ
    Martinez-Suarez, HJ
    Farooqui, M
    Mukhopadhyay, D
    Hughes, DA
    Mukherjee, P
    Gupta, K
    BLOOD, 2005, 106 (11) : 1026A - 1027A