Clear Cell Variant of Solid Pseudopapillary Neoplasm of the Pancreas: A Report of a Rare Variant and Review of the Literature

被引:0
|
作者
Costales, Cristina [1 ]
Mehta, Arjun [1 ]
Kulkarni, Sujit [1 ]
Larson, Brent K. [1 ,2 ]
机构
[1] Univ Southern Calif, Los Angeles, CA USA
[2] Cedars Sinai Med Ctr, Dept Pathol & Lab Med, Los Angeles, CA 90048 USA
关键词
solid pseudopapillary neoplasm; pancreas; clear cell; pancreas cancer; pseudopapillary; TUMORS;
D O I
10.1177/1066896919833790
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
The clear cell variant of solid pseudopapillary neoplasm (ccSPN) of the pancreas was first described in 2006. In this article, we report a case of this rare variant and review the few published reports. Both the current and previous reports show that ccSPN has several morphologic differences from conventional SPN, including clear vacuoles, fewer pseudopapillary formations, more solid/diffuse architecture, less hemorrhage, and fewer cholesterol clefts. Some of these features peculiar to ccSPN, such as solid/diffuse architecture, have been proposed to suggest aggressive behavior, though reports of ccSPN are rare and often have limited clinical follow-up. ccSPN also appears to occur more frequently in males than conventional SPNs. These clinical and pathologic features lead to unique set of differential diagnostic considerations for ccSPN, including metastatic renal cell carcinoma, perivascular epithelial cell tumor, and clear cell variants of other carcinomas. These unique features, atypical differential, and uncertain prognostic ramifications all make ccSPN an important variant to be aware of and report.
引用
收藏
页码:535 / 540
页数:6
相关论文
共 50 条
  • [41] Solid pseudopapillary neoplasm of the pancreas presenting as acute pancreatitis at the emergency department: A case report and review of literature
    Perillo, Engelbert Simon Sy
    Chan, Melchor Mesa
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2018, 33 : 536 - 536
  • [42] Solid pseudopapillary neoplasm of the pancreas
    Sharma, Ishna
    Cho, Woo Cheal
    Thaker, Shefali
    Jensen, Todd
    Balarezo, Fabiola
    Weiss, Richard
    Finck, Christine
    JOURNAL OF PEDIATRIC SURGERY CASE REPORTS, 2018, 37 : 63 - 69
  • [43] Solid pseudopapillary neoplasm of the pancreas
    Jimenez-Fuertes, Montiel
    Ramon Ramirez-Garcia, Jose
    Ruiz-Tovar, Jaime
    Diaz Garcia, Gustavo
    Duran-Poveda, Manuel
    CIRUGIA ESPANOLA, 2016, 94 (02): : E31 - E33
  • [44] Solid pseudopapillary neoplasm of pancreas
    Biswas, Rituparna
    Ghosh, Anshuman
    CLINICAL CANCER INVESTIGATION JOURNAL, 2015, 4 (06): : 723 - 725
  • [45] Clear Cell Atypical Fibroxantoma: A Rare Variant of Atypical Fibroxanthoma and Review of the Literature
    Bedir, Recep
    Agirbas, Sule
    Sehitoglu, Ibrahim
    Yurdakul, Coneyt
    Elmas, Omer
    JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2014, 8 (06) : FD9 - FD11
  • [46] Solid pseudopapillary neoplasm of the pancreas
    Ayo O Omiyale
    World Journal of Hepatology, 2021, (08) : 896 - 903
  • [47] Solid pseudopapillary neoplasm of the pancreas
    Omiyale, Ayo O.
    WORLD JOURNAL OF HEPATOLOGY, 2021, 13 (08) : 896 - 903
  • [48] SOLID PSEUDOPAPILLARY NEOPLASM OF THE PANCREAS
    Marcante Carlotto, Jorge Roberto
    Apodaca Torrez, Franz Robert
    Gonzalez, Adriano Miziara
    Linhares, Marcelo Moura
    Trivino, Tarcisio
    Herani-Filho, Benedito
    Goldenberg, Alberto
    Lopes-Filho, Gaspar de Jesus
    Lobo, Edson Jose
    ABCD-ARQUIVOS BRASILEIROS DE CIRURGIA DIGESTIVA-BRAZILIAN ARCHIVES OF DIGESTIVE SURGERY, 2016, 29 (02): : 93 - 96
  • [49] Solid Pseudopapillary Neoplasm of the Pancreas
    Garkalne, Ieva
    Brussaard, Carola
    JOURNAL OF THE BELGIAN SOCIETY OF RADIOLOGY, 2016, 100 (01):
  • [50] Solid pseudopapillary neoplasm of the head of the pancreas: A case report
    Erguibi, Driss
    El Berni, Yassine
    Moufakkir, Aziz
    Boufettal, Rachid
    Saad, Rifki Jai
    Chehab, Farid
    ANNALS OF MEDICINE AND SURGERY, 2021, 69