Ebola Virus Replication Stands Out

被引：1
|
作者：
Wang, Wenjie [1 ]
Wu, Chao [1 ]
Amarasinghe, Gaya K. [1 ]
Leung, Daisy W. [1 ,2 ]
机构：
[1] Washington Univ, Dept Pathol & Immunol, Sch Med St Louis, St Louis, MO 63110 USA
[2] Washington Univ, Dept Med, Sch Med St Louis, St Louis, MO 63110 USA
来源：
TRENDS IN MICROBIOLOGY | 2019年 / 27卷 / 07期
关键词：
RNA-SYNTHESIS; INITIATION; MECHANISM;
D O I：
10.1016/j.tim.2019.05.004
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A recent study by Deflube et al. (Proc. Natl Acad. Sci. U. S. A. 2019; 116: 8535-8543) reported that Ebola virus genomes have variable 3' terminal nucleotides. This finding is a departure from other nonsegmented, negative-strand RNA viruses (NNSVs) that have been studied to date and has broad implications for filoviral replication and innate immune evasion.
引用
收藏
页码：565 / 566
页数：2
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