Aminohydroxylation and dihydroxylation of 4-aryl-1,2,5,6-tetrahydropyridines

被引：7
|
作者：
Chang, Meng-Yang [1 ]
Lin, Chun-Yu
Wu, Tsun-Cheng
机构：
[1] Natl Univ Kaohsiung, Dept Appl Chem, Kaohsiung 811, Taiwan
[2] Natl Sun Yat Sen Univ, Dept Chem, Kaohsiung 804, Taiwan
来源：
TETRAHEDRON LETTERS | 2006年 / 47卷 / 31期
关键词：
cerium ammonium nitrate; oxidative addition; hydrogenation; 4-aryl-1,2,5,6-tetrahydropyridines; aminohydroxylation; dihydroxylation;
D O I：
10.1016/j.tetlet.2006.05.174
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Substituted 3-amino-4-aryl-4-liydi-oxypiperidines and 4-aryl-3.4-dihvdroxypiperidiiies are synthesized in the modest overall yields starting from the regio- and stereoselective trans-aminohydroxylation and dihydroxylation of 4-aryl-1,15.6-tetrahydropyridines via CAN-mediated oxidative addition and hydrogenation. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：5445 / 5449
页数：5
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