Diagnostic utility of the risk of malignancy index for borderline ovarian tumors

Purpose of investigation: To determine the best cutoff value for the risk of malignancy index (RMI) by comparing the four malignancy risk indices (RMI 1, RMI 2, RMI 3, and RMI 4) in patients with borderline ovarian tumors (BOTs). Materials and Methods: The authors enrolled 510 patients in this retrospective study: 76 women with BOTs and 434 with benign adnexal masses. There were no restrictions in BOT histotypes. Results: The area under the curves for RMI 1, RMI 2, RMI 3, and RMI 4 were 0.742, 0.755, 0.765, and 0.787, respectively. RMI 4 performed better in diagnosing BOT preoperatively than RMI 1, RMI 2, and RMI 3, at a cutoff value of 190. Conclusion: RMI 4 at a cutoff value of 190 can be successfully used for identifying patients with suspected BOTs who require specialist referral.