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Urologic applications of botulinum toxin
被引:7
|作者:
King, Ashley
[1
]
Quirouet, Adrienne
[1
]
Moore, Courtenay K.
[2
,3
,4
]
机构:
[1] Cleveland Clin, Glickman Urol Inst, Female Pelv Med & Reconstruct Surg, Cleveland, OH 44195 USA
[2] Case Western Reserve Univ, Cleveland Clin Lerner Coll Med, Female Pelv Med & Reconstruct Surg, Glickman Urol Inst, Cleveland, OH 44106 USA
[3] Case Western Reserve Univ, Cleveland Clin Lerner Coll Med, Female Pelv Med & Reconstruct Surg, Cleveland, OH 44106 USA
[4] Case Western Reserve Univ, Cleveland Clin Lerner Coll Med, Urol, Cleveland, OH 44106 USA
关键词:
NEUROGENIC DETRUSOR OVERACTIVITY;
PLACEBO-CONTROLLED TRIAL;
LOWER URINARY-TRACT;
QUALITY-OF-LIFE;
CORD-INJURY PATIENTS;
SPHINCTER DYSSYNERGIA;
DOUBLE-BLIND;
A TOXIN;
BLADDER;
INCONTINENCE;
D O I:
10.3949/ccjm.82a.13166
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
The neuromuscular blocker botulinum toxin has a wide variety of medical applications, including overactive bladder and neurogenic detrusor overactivity in patients in whom drug therapy fails or is not well tolerated. Botulinum toxin therapy for these conditions has been shown to be safe and effective in several large multicenter randomized controlled trials. Off-label uses in urology include detrusor external sphincter dyssynergia and pelvic pain syndromes.
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页码:456 / 464
页数:9
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