THE JAK INHIBITOR (BARICITINIB) INHIBITS IFNΓ-INDUCED GLIOSTATIN EXPRESSION IN HUMAN FIBROBLAST-LIKE SYNOVIOCYTES

被引：1
|
作者：
Joyo, Yuji [1 ]
Waguri-Nagaya, Yuko [2 ]
Kawaguchi, Yohei [1 ,3 ]
Oguri, Yusuke [1 ]
Nozaki, Masahiro [1 ]
Asai, Kiyofumi [3 ]
机构：
[1] Nagoya City Univ, Grad Sch Med Sci, Dept Orthopaed Surg, Nagoya, Aichi, Japan
[2] Nagoya City Univ, Grad Sch Med Sci, Dept Joint Surg Rheumat Dis, Nagoya, Aichi, Japan
[3] Nagoya City Univ, Grad Sch Med Sci, Dept Mol Neurobiol, Nagoya, Aichi, Japan
来源：
ANNALS OF THE RHEUMATIC DISEASES | 2019年 / 78卷
基金：
日本学术振兴会;
关键词：
D O I：
10.1136/annrheumdis-2019-eular.4617
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
AB0066
引用
收藏
页码：1497 / 1497
页数：1
相关论文
共 50 条
  • [41] FK506 inhibition of gliostatin/thymidine phosphorylase production induced by tumor necrosis factor-α in rheumatoid fibroblast-like synoviocytes
    Takaya Yamagami
    Yuko Waguri-Nagaya
    Kenji Ikuta
    Mineyoshi Aoyama
    Kiyofumi Asai
    Takanobu Otsuka
    Rheumatology International, 2011, 31 : 903 - 909
  • [42] Potentiation of TNF-Induced T Cell Chemokine Expression by Type I Interferon in Fibroblast-Like Synoviocytes: Target for JAK Inhibition
    Rosengren, Sanna
    Firestein, Gary S.
    Boyle, David L.
    ARTHRITIS AND RHEUMATISM, 2011, 63 (10): : S707 - S707
  • [43] Acacetin inhibits expression of matrix metalloproteinases via a MAPK-dependent mechanism in fibroblast-like synoviocytes
    Chen, Wei-Ping
    Yang, Zhi-Gao
    Hu, Peng-Fei
    Bao, Jia-Peng
    Wu, Li-Dong
    JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2015, 19 (08) : 1910 - 1915
  • [44] The antifibrotic drug pirfenidone inhibits spondyloarthritis fibroblast-like synoviocytes and osteoblasts in vitro
    Stougaard J.
    Lomholt S.
    Ommen P.
    Kelsen J.
    Kragstrup T.W.
    BMC Rheumatology, 2 (1) : 1 - 9
  • [45] TARGETED INHIBITION OF JANUS KINASES ABATES IFN-GAMMA-INDUCED INVASIVE BEHAVIOR OF FIBROBLAST-LIKE SYNOVIOCYTES
    Karonitsch, T.
    Beckmann, D.
    Dalwigk, K.
    Byrne, R.
    Niederreiter, B.
    Holinka, J.
    Sevelda, F.
    Korb-Pap, A.
    Steiner, G.
    Smolen, J.
    Pap, T.
    Kiener, H.
    ANNALS OF THE RHEUMATIC DISEASES, 2017, 76 : 486 - 486
  • [46] Kaempferitrin inhibits proliferation, induces apoptosis, and ameliorates inflammation in human rheumatoid arthritis fibroblast-like synoviocytes
    Wang, Jing
    Zhao, Qing
    PHYTOTHERAPY RESEARCH, 2019, 33 (06) : 1726 - 1735
  • [47] EFFECTS AND MECHANISMS OF UPAR EXPRESSION IN RHEUMATOID ARTHRITIS FIBROBLAST-LIKE SYNOVIOCYTES
    Yunfeng, P.
    Yan, L.
    ANNALS OF THE RHEUMATIC DISEASES, 2014, 73 : 849 - 849
  • [48] Cyanidin-3-glucoside inhibits inflammatory activities in human fibroblast-like synoviocytes and in mice with collagen-induced arthritis
    Sun, Yan
    Li, Lingling
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2018, 45 (10): : 1038 - 1045
  • [49] Silencing CoREST inhibits the viability and migration of fibroblast-like synoviocytes in TNF-α-induced rheumatoid arthritis
    Yu, Ziliang
    Chen, Feihu
    Liu, Hao
    Fan, Jianbo
    Ding, Xiaomin
    Zhu, Xinhui
    Cui, Shengyu
    Yi, Hong
    Zhou, Xiaogang
    Hu, Yalong
    Liu, Wei
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2022, 23 (02)
  • [50] Chrysoeriol suppresses hyperproliferation of rheumatoid arthritis fibroblast-like synoviocytes and inhibits JAK2/STAT3 signaling
    Jia-Ying Wu
    Ying-Jie Chen
    Xiu-Qiong Fu
    Jun-Kui Li
    Ji-Yao Chou
    Cheng-Le Yin
    Jing-Xuan Bai
    Ying Wu
    Xiao-Qi Wang
    Amy Sze-man Li
    Lut Yi Wong
    Zhi-Ling Yu
    BMC Complementary Medicine and Therapies, 22
12345