Is vitamin D supplementation a viable treatment for Crohn's disease?

被引:4
|
作者
O'Sullivan, Maria [1 ]
机构
[1] Univ Dublin Trinity Coll, Dept Clin Med, Ctr Hlth Sci, St Jamess Hosp, Dublin 8, Ireland
关键词
Vitamin D; 25-hydroxyvitamin D (25OHD); Crohn's disease (CD); randomized controlled trial (RCT); dietary supplements; INFLAMMATORY-BOWEL-DISEASE; RANDOMIZED CONTROLLED-TRIAL; DOUBLE-BLIND; D DEFICIENCY; THERAPY;
D O I
10.1586/17474124.2016.1120157
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Vitamin D, important for maintaining bone health in Crohn's disease (CD), may have potential as a treatment for the core inflammatory disease process. There is plausible evidence in favor of vitamin D as an anti-inflammatory from animal models, epidemiological and cross sectional studies of CD. Few clinical trials, however, have been published and therefore the translation of this promise into clinical benefit for people with CD remains unclear. The purpose of this piece is to consider the viability of vitamin D as a treatment for CD based on the current available evidence.
引用
收藏
页码:1 / 4
页数:4
相关论文
共 50 条
  • [41] Treatment of vitamin D deficiency due to Crohn's disease with tanning bed ultraviolet B radiation
    Koutkia, P
    Lu, ZR
    Chen, TC
    Holick, MF
    GASTROENTEROLOGY, 2001, 121 (06) : 1485 - 1488
  • [42] A randomised trial of intravenous pamidronate and calcium & vitamin D in the treatment of osteoporosis associated with Crohn's disease
    Bartram, SA
    Francis, RM
    Thompson, NP
    GASTROENTEROLOGY, 2001, 120 (05) : A627 - A627
  • [43] A randomised trial of intravenous pamidronate and calcium & vitamin D in the treatment of osteoporosis associated with Crohn's disease
    Bartram, SA
    Francis, RM
    Thompson, NP
    GUT, 2001, 48 : A1 - A1
  • [44] Evaluation of Vitamin D Supplementation in Moderate to Severe Crohn's Disease Patients Using Anti-TNF: Replacement or Immunomodulation?
    Bafutto, Mauro
    Oliveira, Enio
    Costa, Michelle
    Silva, Karen
    Costa, Juliana
    Bafutto, Eduardo
    Bafuttok, Alexandre
    Resende Filho, Joffre
    INFLAMMATORY BOWEL DISEASES, 2017, 23 : S40 - S40
  • [45] Influence of Vitamin D3 Supplementation on Infliximab Effectiveness in Chinese Patients With Crohn's Disease: A Retrospective Cohort Study
    Xia, Sheng-long
    Min, Quan-jia
    Shao, Xiao-xiao
    Lin, Dao-po
    Ma, Guo-long
    Wu, Hao
    Cao, Shu-guang
    Jiang, Yi
    FRONTIERS IN NUTRITION, 2021, 8
  • [46] Impact of high-dose vitamin D3 supplementation in treatment of Crohn's disease in remission: a randomised double-blind controlled study
    Narula, N.
    Cooray, M.
    Anglin, R.
    Muqtadir, Z.
    Narula, A.
    Marshall, J.
    JOURNAL OF CROHNS & COLITIS, 2016, 10 : S429 - S430
  • [47] Vitamin D supplementation may improve symptoms in Meniere's disease
    Bueki, Bela
    Juenger, Heinz
    Lundberg, Yunxia Wang
    MEDICAL HYPOTHESES, 2018, 116 : 44 - 46
  • [48] There is no evidence that vitamin D supplementation drives the progression of Alzheimer's disease
    Gombart, Adrian F. F.
    Michels, Alexander J. J.
    Eggersdorfer, Manfred
    AGING CELL, 2023, 22 (01)
  • [49] Antioxidant vitamin supplementation in Crohn's disease decreases oxidative stress: A randomized controlled trial
    Aghdassi, E
    Wendland, BE
    Steinhart, AH
    Wolman, SL
    Jeejeebhoy, K
    Allard, JP
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2003, 98 (02): : 348 - 353
  • [50] Fatty acid and vitamin D status in the EPIC trials of Crohn disease treatment
    Plotnikoff, Gregory A.
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2008, 300 (06): : 650 - 650