AG-120 (ivosidenib), a first in-class mutant IDH1 inhibitor, promotes morphologic changes and upregulates liver-specific genes in IDH1 mutant cholangiocarcinoma

被引:3
|
作者
Ishii, Yuko [1 ]
Sigel, Carlie [2 ]
Lowery, Maeve A. [2 ]
Goyal, Lipika [3 ]
Gliser, Camelia [1 ]
Jiang, Liewen [1 ]
Pandya, Susan [1 ]
Bin Wu [1 ]
Choe, Sung [1 ]
Deshpande, Vikram [3 ]
机构
[1] Agios Pharmaceut Inc, Cambridge, MA USA
[2] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
[3] Massachusetts Gen Hosp, Boston, MA 02114 USA
关键词
D O I
10.1158/1535-7163.TARG-17-A071
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A071
引用
收藏
页数:2
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