Comment on "In Silico Modeling of Gastrointestinal Drug Absorption: Predictive Performance of Three Physiologically-Based Absorption Models"

被引:8
|
作者
Turner, David B. [1 ]
Liu, Bo [1 ]
Patel, Nikunjkumar [1 ]
Pathak, Shriram M. [1 ]
Polak, Sebastian [1 ,2 ]
Jamei, Masoud [1 ]
Dressman, Jennifer [4 ]
Rostami-Hodjegan, Amin [1 ,3 ]
机构
[1] Simcyp Ltd, Blades Enterprise Ctr, John St, Sheffield S2 4SU, S Yorkshire, England
[2] Jagiellonian Univ, Coll Med, Fac Pharm, Krakow, Poland
[3] Univ Manchester, Manchester Pharm Sch, Manchester M13 9PT, Lancs, England
[4] Goethe Univ, Fac Biochem Chem & Pharm, Frankfurt, Germany
关键词
FEXOFENADINE; BIOAVAILABILITY; VOLUMES; TRANSIT; HUMANS; VITRO; WATER;
D O I
10.1021/acs.molpharmaceut.6b00469
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
引用
收藏
页码:336 / 339
页数:4
相关论文
共 50 条
  • [31] Maximizing the Role of Physiologically Based Oral Absorption Modeling in Generic Drug Development
    Mitra, Amitava
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2019, 105 (02) : 307 - 309
  • [32] Utility of Physiologically Based Absorption Modeling in Implementing Quality by Design in Drug Development
    Zhang, Xinyuan
    Lionberger, Robert A.
    Davit, Barbara M.
    Yu, Lawrence X.
    AAPS JOURNAL, 2011, 13 (01): : 59 - 71
  • [33] Utility of Physiologically Based Absorption Modeling in Implementing Quality by Design in Drug Development
    Xinyuan Zhang
    Robert A. Lionberger
    Barbara M. Davit
    Lawrence X. Yu
    The AAPS Journal, 2011, 13 : 59 - 71
  • [34] GASTROINTESTINAL ABSORPTION OF XENOBIOTICS IN PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELS - A 2-COMPARTMENT DESCRIPTION
    STAATS, DA
    FISHER, JW
    CONNOLLY, RB
    DRUG METABOLISM AND DISPOSITION, 1991, 19 (01) : 144 - 148
  • [35] Physiologically-Based Pharmacokinetic Modeling of Macitentan: Prediction of Drug-Drug Interactions
    de Kanter, Ruben
    Sidharta, Patricia N.
    Delahaye, Stphane
    Gnerre, Carmela
    Segrestaa, Jerome
    Buchmann, Stephan
    Kohl, Christopher
    Treiber, Alexander
    CLINICAL PHARMACOKINETICS, 2016, 55 (03) : 369 - 380
  • [36] Application of Physiologically Based Absorption Modeling for Amphetamine Salts Drug Products in Generic Drug Evaluation
    Babiskin, Andrew H.
    Zhang, Xinyuan
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, 104 (09) : 3170 - 3182
  • [37] Biorelevant dissolution testing and physiologically based absorption modeling to predict in vivo performance of supersaturating drug delivery systems
    Thakore, Samarth
    Sirvi, Arvind
    Joshi, Vikram C.
    Panigrahi, Sanjali S.
    Manna, Arijita
    Singh, Ridhima
    Sangamwar, Abhay
    Bansal, Arvind K.
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2021, 607
  • [38] Physiologically-based pharmacokinetic models to predict drug exposure during pregnancy
    Ait-Chikh, Celia
    Page, Guylene
    Thoreau, Vincent
    ANNALES PHARMACEUTIQUES FRANCAISES, 2024, 82 (02): : 236 - 242
  • [39] Physiologically-based modeling of monoclonal antibody pharmacokinetics in drug discovery and development
    Glassman, Patrick M.
    Balthasar, Joseph P.
    DRUG METABOLISM AND PHARMACOKINETICS, 2019, 34 (01) : 3 - 13
  • [40] Incorporation of in vitro drug metabolism data into physiologically-based pharmacokinetic models
    Houston, JB
    Carlile, DJ
    TOXICOLOGY IN VITRO, 1997, 11 (05) : 473 - 478