A convenient one-pot synthesis of polysubstituted pyrroles from N-protected succinimides

被引：10
|
作者：
Kobeissi, Marwan [1 ]
Yazbeck, Ogaritte [2 ]
Chreim, Yamama [3 ]
机构：
[1] Lebanese Univ, Lab Synth Organ, Equipe Physiotox Environm, Fac Sci,Dept Chem,Sect 5, Hadath, Lebanon
[2] Lebanese Univ, Lab Synth Organ, Fac Sci, Dept Chem,Sect 1, Hadath, Lebanon
[3] Lebanese Univ, Lab Synth Organ, Fac Sci, Dept Chem,Sect 5, Hadath, Lebanon
来源：
TETRAHEDRON LETTERS | 2014年 / 55卷 / 15期
关键词：
Dienamines; Petasis reagent; Methylenation; Succinimides; Polysubstituted pyrroles; MEDIATED CARBONYL OLEFINATIONS; METHYLENATIONS; ALKALOIDS;
D O I：
10.1016/j.tetlet.2014.03.021
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The dienamine products formed by the reaction between polysubstituted succinimides and the Petasis reagent were subjected to isomerization under mild acidic conditions to give polysubstituted pyrroles in excellent yields (85-95%). The scope and limitations of this methodology are explored. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：2523 / 2526
页数：4
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