Correlation of islet infiltration to gene expression of blood mononuclear cells and pancreas draining lymph nodes in the LEW.1AR1-iddm rat model of autoimmune diabetes

被引:0
|
作者
Schoeppe, T. [1 ]
Weiss, H. [1 ]
Wedekind, D. [2 ]
Schmidt, R. [3 ]
Tiedge, M. [1 ]
机构
[1] Univ Rostock, IBIO, D-18055 Rostock, Germany
[2] Hannover Med Sch, Hannover, Germany
[3] Univ Rostock, IBIMA, D-18055 Rostock, Germany
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
552
引用
收藏
页码:S227 / S227
页数:1
相关论文
共 50 条
  • [41] Immunomodulatory therapies with anti-IL-6 and anti-IL-17 combined with anti-TCR to regain normoglycaemia in the LEW.1AR1-iddm rat as a model for human type 1 diabetes
    Joerns, A.
    Teraoku, H.
    Yoshimoto, T.
    Wedekind, D.
    Lenzen, S.
    DIABETOLOGIA, 2018, 61 : S212 - S212
  • [42] Pathology of the pancreas and other organs in the diabetic LEW.1AR1/Ztm-iddm rat, a new model of spontaneous insulin-dependent diabetes mellitus
    Jörns, A
    Kubat, B
    Tiedge, M
    Wedekind, D
    Hedrich, HJ
    Klöppel, G
    Lenzen, S
    VIRCHOWS ARCHIV, 2004, 444 (02) : 183 - 189
  • [43] Pathology of the pancreas and other organs in the diabetic LEW.1AR1/Ztm-iddm rat, a new model of spontaneous insulin-dependent diabetes mellitus
    Anne Jörns
    Birgit Kubat
    Markus Tiedge
    Dirk Wedekind
    Hans-Jürgen Hedrich
    Günter Klöppel
    Sigurd Lenzen
    Virchows Archiv, 2004, 444 : 183 - 189
  • [44] CD4 immunomodulation by monoclonal RIB5/2 antibody in LEW.1AR1-iddm rats: long-term protection against islet infiltration and beta cell destruction
    Schoeppe, T.
    Weiss, H.
    Pagel, R.
    Tiedge, M.
    DIABETOLOGIA, 2016, 59 : S224 - S225
  • [45] Islet inflammation and T-CELL autoreactivity in pancreas-draining lymph nodes during recent onset type 1 diabetes
    Dotta, F.
    Van Halteren, A. G. S.
    Bonato, V.
    Vendrame, F.
    Marchetti, P.
    Roep, B. O.
    ACTA DIABETOLOGICA, 2007, 44 : S12 - S12
  • [46] A novel Dock8 gene mutation confers diabetogenic susceptibility in the LEW.1AR1/Ztm-iddm rat, an animal model of human type 1 diabetes
    Arndt, Tanja
    Wedekind, Dirk
    Joerns, Anne
    Tsiavaliaris, Georgios
    Cuppen, Edwin
    Hedrich, Hans-Juergen
    Lenzen, Sigurd
    DIABETOLOGIA, 2015, 58 (12) : 2800 - 2809
  • [47] A novel Dock8 gene mutation confers diabetogenic susceptibility in the LEW.1AR1/Ztm-iddm rat, an animal model of human type 1 diabetes
    Tanja Arndt
    Dirk Wedekind
    Anne Jörns
    Georgios Tsiavaliaris
    Edwin Cuppen
    Hans-Jürgen Hedrich
    Sigurd Lenzen
    Diabetologia, 2015, 58 : 2800 - 2809
  • [48] Advanced Glycation End-Products (AGEs) of Lysine and Effects of Anti-TCR/Anti-TNF-α Antibody-Based Therapy in the LEW.1AR1-iddm Rat, an Animal Model of Human Type 1 Diabetes
    Baskal, Svetlana
    Tsikas, Stefanos A.
    Begou, Olga
    Bollenbach, Alexander
    Lenzen, Sigurd
    Joerns, Anne
    Tsikas, Dimitrios
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (03)
  • [49] Onset and progression of infiltration in the islets of Langerhans of the spontaneously diabetic LEW.1AR1/Ztm-iddm rat, a new animal model of T1DM
    Joerns, A
    Günther, A
    Wedekind, D
    Hedrich, HJ
    Lenzen, S
    DIABETOLOGIA, 2003, 46 : A189 - A190
  • [50] Taurine Transporter Gene Expression in Mononuclear Blood Cells of Type 1 Diabetes Patients
    Napoli, Zaleida
    Seghieri, Giuseppe
    Bianchi, Loria
    Anichini, Roberto
    De Bellis, Alessandra
    Campesi, Ilaria
    Carru, Ciriaco
    Occhioni, Stefano
    Zinellu, Angelo
    Franconi, Flavia
    JOURNAL OF DIABETES RESEARCH, 2016, 2016