Sensing Bad: Are Co-stimulatory CAR-Expressing γδ T Cells Safer?

被引:2
|
作者
Parihar, Robin [1 ]
机构
[1] Texas Childrens Hosp, Baylor Coll Med, Ctr Cell & Gene Therapy, Hematol Oncol Sect, 1102 Bates Ave,Suite 1770-02, Houston, TX 77030 USA
关键词
CANCER-IMMUNOTHERAPY; RECEPTOR; RECOGNITION; IMMUNITY;
D O I
10.1016/j.ymthe.2017.04.012
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:1064 / 1066
页数:4
相关论文
共 50 条
  • [21] A co-stimulatory trap set by myeloid leukemia cells
    Esendagli, Gunes
    ONCOIMMUNOLOGY, 2013, 2 (06)
  • [23] Upregulation of co-stimulatory molecules on CD4+T cells in the patients with pemphigus
    Liu, Z.
    Yuan, H.
    Zeng, W.
    Zheng, J.
    Wang, Y.
    Pan, M.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2014, 134 : S22 - S22
  • [24] Alterations in co-stimulatory receptors: a novel defect in T cells in head and neck cancer
    Baruah, P.
    Lee, M.
    Odutoye, T.
    Williamson, P.
    Hyde, N.
    Kaski, J. C.
    Dumitriu, I. E.
    IMMUNOLOGY, 2010, 131 : 160 - 160
  • [25] Co-stimulatory signaling determines tumor antigen sensitivity and persistence of CAR T cells targeting PSCA plus metastatic prostate cancer
    Priceman, Saul J.
    Gerdts, Ethan A.
    Tilakawardane, Dileshni
    Kennewick, Kelly T.
    Murad, John P.
    Park, Anthony K.
    Jeang, Brook
    Yamaguchi, Yukiko
    Yang, Xin
    Urak, Ryan
    Weng, Lihong
    Chang, Wen-Chung
    Wright, Sarah
    Pal, Sumanta
    Reiter, Robert E.
    Wu, Anna M.
    Brown, Christine E.
    Forman, Stephen J.
    ONCOIMMUNOLOGY, 2018, 7 (02):
  • [26] Co-stimulatory effects of T cell blind panel mAbs
    Waclavicek, M
    Pickl, WF
    Kunig, S
    Majdic, O
    Baumruker, T
    Knapp, W
    TISSUE ANTIGENS, 1996, 48 (4-II): : TC206 - TC206
  • [27] Molecular mechanism of co-stimulatory domains in promoting CAR-T cell anti-tumor efficacy
    Zhao, Wanxin
    Yao, Yizhou
    Li, Qihong
    Xue, Ying
    Gao, Xiaoge
    Liu, Xiangye
    Zhang, Qing
    Zheng, Junnian
    Sun, Shishuo
    BIOCHEMICAL PHARMACOLOGY, 2024, 227
  • [28] T cell responses are governed by avidity and co-stimulatory thresholds
    Bachmann, MF
    Sebzda, E
    Kundig, TM
    Shahinian, A
    Speiser, DE
    Mak, TW
    Ohashi, PS
    EUROPEAN JOURNAL OF IMMUNOLOGY, 1996, 26 (09) : 2017 - 2022
  • [29] Role of Co-stimulatory Molecules in T Helper Cell Differentiation
    Schorer, Michelle
    Kuchroo, Vijay K.
    Joller, Nicole
    CO-SIGNAL MOLECULES IN T CELL ACTIVATION: IMMUNE REGULATION IN HEALTH AND DISEASE, 2019, 1189 : 153 - 177
  • [30] Regulation of T-cell migration by co-stimulatory molecules
    David, R.
    Marelli-Berg, F. M.
    BIOCHEMICAL SOCIETY TRANSACTIONS, 2007, 35 : 1114 - 1118