Rhodium-catalysed 1,4-additions in water:: Synthesis of succinic esters and β2-amino acid derivatives

被引:14
|
作者
Wadsworth, KJ [1 ]
Wood, FK [1 ]
Chapman, CJ [1 ]
Frost, CG [1 ]
机构
[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England
关键词
conjugate addition; rhodium; boronic acids; succinic esters; beta(2)-amino acids;
D O I
10.1055/s-2004-830880
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The rhodium-catalysed addition of boronic acids to alpha-substituted activated alkenes proceeds smoothly in water resulting in a unique synthesis of both succinic esters and beta(2)-amino acid derivatives.
引用
收藏
页码:2022 / 2024
页数:3
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