Mild and efficient rhodium-catalyzed deoxygenation of ketones to alkanes

被引:15
|
作者
Argouarch, Gilles [1 ]
机构
[1] Univ Rennes, CNRS, UMR 6226, ISCR, F-35000 Rennes, France
关键词
AZIDE-ALKYNE CYCLOADDITION; REDUCTIVE DEOXYGENATION; AROMATIC KETONES; ARYL KETONES; ALDEHYDES; HYDROGENOLYSIS; HYDROGENATION; ALCOHOLYSIS; ENONES;
D O I
10.1039/c9nj02954k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A new and simple method for the deoxygenation of ketones to alkanes is presented. Most substrates are reduced under mild conditions by triethylsilane in the presence of catalytic amounts of [Rh(mu-Cl)(CO)(2)](2). This system selectively provides the methylene hydrocarbons in good to excellent yields starting from acetophenones and diaryl ketones. A rapid examination of the reaction pathway suggests that the ketone is first converted into an alcohol, which then undergoes hydrogenolysis to give the alkane.
引用
收藏
页码:11041 / 11044
页数:4
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