Optically Pure C1-Symmetric Cyclic(alkyl)(amino)carbene Ruthenium Complexes for Asymmetric Olefin Metathesis

被引：31

作者：

Morvan, Jennifer ^{[1
]}

Vermersch, Francois ^{[2
]}

Zhang, Ziyun ^{[3
]}

Falivene, Laura ^{[4
]}

Vives, Thomas ^{[1
]}

Dorcet, Vincent ^{[1
]}

Roisnel, Thierry ^{[1
]}

Crevisy, Christophe ^{[1
]}

Cavallo, Luigi ^{[3
]}

Vanthuyne, Nicolas ^{[5
]}

Bertrand, Guy ^{[2
]}

Jazzar, Rodolphe ^{[2
]}

Mauduit, Marc ^{[1
]}

机构：

[1] Univ Rennes, CNRS, Ecole Natl Super Chim Rennes, ISCR UMR 6226, F-35000 Rennes, France

[2] Univ Calif San Diego, Dept Chem & Biochem, UCSD CNRS Joint Res Chem Lab UMI 3555, La Jolla, CA 92093 USA

[3] King Abdullah Univ Sci & Technol KAUST, KAUST Catalysis Ctr KCC, Thuwal 239556900, Saudi Arabia

[4] Univ Salerno, Dipartimento Chim & Biol, I-84100 Fisiciano, Italy

[5] Aix Marseille Univ, CNRS, F-13397 Marseille, France

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2020年 / 142卷 / 47期

关键词：

N-HETEROCYCLIC CARBENES; CYCLIC (ALKYL)(AMINO)CARBENES CAACS; CATALYSTS; MECHANISM; BEARING; LIGANDS; REACTIVITY;

D O I：

10.1021/jacs.0c10705

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An expedient access to the first optically pure ruthenium complexes containing C-1-symmetric cyclic (alkyl)(amino)carbene ligands is reported. They demonstrate excellent catalytic performances in asymmetric olefin metathesis with high enantioselectivities (up to 92% ee). Preliminary mechanistic insights provided by density functional theory models highlight the origin of the enantioselectivity.

引用

页码：19895 / 19901

页数：7

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