Anesthesia-induced epilepsy: causes and treatment

被引:6
|
作者
Zhao, Xiaojuan [1 ]
Wang, Xuefeng [1 ]
机构
[1] Chongqing Med Univ, Dept Neurol, Affiliated Hosp 1, Chongqing 400016, Peoples R China
关键词
anesthesia; anesthetic; epilepsy; epileptic seizure; mechanism; LIDOCAINE-INDUCED SEIZURES; INTRAOPERATIVE ELECTROCORTICOGRAPHY; SEVOFLURANE ANESTHESIA; VOLATILE ANESTHETICS; STATUS EPILEPTICUS; CORTICAL-NEURONS; SPIKE ACTIVITY; K+ CHANNEL; RAT MODEL; PROPOFOL;
D O I
10.1586/14737175.2014.948851
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Epilepsy is a type of chronic brain disease that results from an abnormally high synchronization of neuronal discharge. The typical clinical features of epilepsy are paroxysms and transient and stereotyped brain dysfunction. Many cases of epileptic seizures occurring during anesthesia have been reportedx. Recently, risk assessment of epileptic seizures during surgery and anesthesia has gained increasing attention. In this review, we systematically summarize the influence of anesthesia on epileptic seizures; the types, durations and frequencies of seizures related to anesthesia; and the epidemiology, prevention, treatment and prognosis of epilepsy. We also explore the possible mechanism of epilepsy and provide guidance for anesthesia during surgeries.
引用
收藏
页码:1099 / 1113
页数:15
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