Recombinant human, active site-blocked factor VIIa reduces infarct size and the no-reflow phenomenon in a rabbit model of myocardial ischemia and reperfusion

被引:0
|
作者
Golino, P
Ragni, M
Cirillo, P
Ravera, A
Buono, G
Piro, O
Botticella, F
Ezban, M
Chiariello, M
机构
[1] Univ Naples Federico II, Div Cardiol, Naples, Italy
[2] Novo Nordisk AS, Dept Vessel Wall Biol, DK-2820 Gentofte, Denmark
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
1481
引用
收藏
页码:468 / 468
页数:1
相关论文
共 50 条
  • [21] Long-term antithrombotic effects of human recombinant, active site-blocked factor VII in a chronic rabbit model of intravascular thrombosis.
    Golino, P
    Cirillo, P
    D'Andrea, D
    Ragni, M
    Calabr, P
    Ravera, M
    Tommasini, P
    Ezban, M
    Chiariello, M
    CIRCULATION, 1998, 98 (17) : 727 - 727
  • [22] Effects of SBT-255 on Myocardial Infarct Size and No Reflow in a Rat Myocardial Ischemia/Reperfusion Model
    Dai, Wangde
    Brown, David A.
    Kloner, Robert A.
    CIRCULATION, 2022, 146
  • [23] Effects of Op2113 on Myocardial Infarct Size and No Reflow in a Rat Myocardial Ischemia/reperfusion Model
    Dai, Wangde
    Le Grand, Bruno
    Boucard, Aurelie
    Carreno, Juan
    Zhao, Lifu
    Kloner, Robert A.
    CIRCULATION, 2020, 142
  • [24] Effects of OP2113 on Myocardial Infarct Size and No Reflow in a Rat Myocardial Ischemia/Reperfusion Model
    Dai, Wangde
    Amoedo, Nivea Dias
    Perry, Justin
    Le Grand, Bruno
    Boucard, Aurelie
    Carreno, Juan
    Zhao, Lifu
    Brown, David A.
    Rossignol, Rodrigue
    Kloner, Robert A.
    CARDIOVASCULAR DRUGS AND THERAPY, 2022, 36 (02) : 217 - 227
  • [25] Effects of OP2113 on Myocardial Infarct Size and No Reflow in a Rat Myocardial Ischemia/Reperfusion Model
    Wangde Dai
    Nivea Dias Amoedo
    Justin Perry
    Bruno Le Grand
    Aurelie Boucard
    Juan Carreno
    Lifu Zhao
    David A. Brown
    Rodrigue Rossignol
    Robert A. Kloner
    Cardiovascular Drugs and Therapy, 2022, 36 : 217 - 227
  • [26] Active site inhibited factor VIIa attenuates myocardial ischemia/reperfusion injury in mice
    Loubele, S. T. B. G.
    Spek, C. A.
    Leenders, P.
    Van Oerle, R.
    Aberson, H. L.
    Van der Voort, D.
    Hamulyak, K.
    Petersen, L. C.
    Spronk, H. M. H.
    Ten Cate, H.
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2009, 7 (02) : 290 - 298
  • [27] Postconditioning fails to improve no reflow or alter infarct size in an open-chest rabbit model of myocardial ischemia-reperfusion
    Hale, Sharon L.
    Mehra, Ankur
    Leeka, Justin
    Kloner, Robert A.
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2008, 294 (01): : H421 - H425
  • [28] Active site inhibited factor VIIa reduces myocardial infarct size after ischaemia/reperfusion injury in mice via tissue factor/NFkappaB-mediated mechanisms
    Loubele, STBG
    Frederix, K
    Leenders, P
    Van Oerle, R
    Hamulyak, K
    Spek, CA
    Spronk, HMH
    Van der Voort, D
    Ten Cate, H
    BRITISH JOURNAL OF HAEMATOLOGY, 2006, 133 : 25 - 25
  • [29] Impact of electrical defibrillation on infarct size and no-reflow in pigs subjected to myocardial ischemia-reperfusion without and with ischemic conditioning
    Skyschally, Andreas
    Amanakis, Georgios
    Neuhaeuser, Markus
    Kleinbongard, Petra
    Heusch, Gerd
    AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2017, 313 (05): : H871 - H878
  • [30] Relationship between Retrograde Coronary Blood Flow and the Extent of No-Reflow and Infarct Size in a Porcine Ischemia–Reperfusion Model
    Stavros Stavrakis
    John Terrovitis
    Elias Tsolakis
    Stavros Drakos
    Argirios Dalianis
    Michael Bonios
    Dimitrios Koudoumas
    Konstantinos Malliaras
    John Nanas
    Journal of Cardiovascular Translational Research, 2011, 4 : 99 - 105