Synthesis of two novel tricyclic rings:: Triazolo[4,5-g]quinolines and pyrido[2,3-g]quinoxalines derived from 6,7-diaminoquinolines

被引：20

作者：

Sanna, P ^{[1
]}

Carta, A ^{[1
]}

Paglietti, G ^{[1
]}

机构：

[1] Univ Sassari, Dipartimento Farmaco Chim Tossicol, I-07100 Sassari, Italy

来源：

HETEROCYCLES | 2000年 / 53卷 / 02期

关键词：

general simple route; revision of nitration; 2,3-dichloroacetanilide;

D O I：

10.3987/COM-99-8766

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A general simple route for the synthesis of triazolo[4,5-g]quinolines and pyrido[2,3-g]quinoxalines is described. The heterocycles obtained were fully characterised by their spectroscopical properties. A revision of the nitration of the 2,3-dichloroacetanilide is also discussed, since it afforded the request nitro derivative to build up the key intermediate 6,7-diaminoquinolines.

引用

页码：423 / +

页数：11

共 34 条

[21] DIFFERENTIAL INHIBITION BY AN ANTITUMORAL DRUG 10-[GAMMA-DIETHYLAMINOPROPYLAMINO]-6-METHYL-5H-PYRIDO[3',4' - 4,5]PYRROLO [2,3-G]ISOQUINOLINE (BD-40), A PYRIDO-PYRROLO-ISOQUINOLINE DERIVATIVE, OF INVITRO DNA-SYNTHESIS CATALYZED BY VARIOUS DNA-POLYMERASES
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CANCER LETTERS, 1990, 51 (01) : 59 - 65
[22] Novel heteroannulated chromeno[3′,2′:5,6]pyrido[2,3-d][1,2,4]triazolo[4,3-a] pyrimidines and chromeno[3′′,2′′:5′,6′]pyrido[2′,3′:4,5]pyrimido[2,1-c][1,2,4] triazines: Synthesis, characterization and antimicrobial evaluation
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SYNTHETIC COMMUNICATIONS, 2022, 52 (05) : 764 - 773
[23] One-pot synthesis of novel pyrimido[4,5-b]quinolines and pyrido[2,3-d:6,5d']dipyrimidines using encapsulated- γ-Fe2O3 nanoparticles
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JOURNAL OF CHEMICAL SCIENCES, 2015, 127 (11) : 1895 - 1904
[24] One-pot synthesis of novel pyrimido[4,5-b]quinolines and pyrido[2,3-d:6,5d′]dipyrimidines using encapsulated- γ-Fe2O3 nanoparticles
MOONA MOHSENIMEHR
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SIMA ABBASPOUR
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Journal of Chemical Sciences, 2015, 127 : 1895 - 1904
[25] Hantzsch synthesis of bis(pyrido[2,3-d:6,5-d']dipyrimidines), bis(pyrimido[4,5-b]quinolines), and bis(benzo[4,5]imidazo[2,1-b]quinazolines) linked to pyrazole units as novel hybrid molecules
Hawass, Mahmoud A. E.
Sanad, Sherif M. H.
Elwahy, Ahmed H. M.
Abdelhamid, Ismail A.
SYNTHETIC COMMUNICATIONS, 2021, 51 (12) : 1899 - 1912
[26] rac-5-acetyl-6-(4-nitrophenyl)-6,7-dihydro-5H-1,3-dioxolo[4,5-g]quinoline-8-one:: chains of rings built from C-H ••• O and C-H ••• π(arene) hydrogen bonds
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ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2004, 60 : O1057 - O1059
[27] SYNTHESIS OF 5,6,6A,7,7A,12A-HEXAHYDRO-4H-BENZO[D,E]BENZOTHIENO-[2,3-G]QUINOLINES AND OF 8-PHENYL-2,3,7,8,9,9A-HEXAHYDRO-1H-BENZO[D,E]QUINOLINES
COPP, FC
FRANZMANN, KW
GILMORE, J
WHALLEY, WB
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1983, (05): : 909 - 914
[28] Facile Synthesis and Properties of new (4-Substituted-phehyl)azo-pyrido[2′,3′:4,5]thieno[2,3-d]pyrimidin-6-(5H)-one Dyes derived from Thioxopyrimidine
Ho, Yuh-Wen
JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN, 2014, 36 (01): : 123 - 130
[29] LIKELIHOOD OF THE NEW ANTI-TUMORAL DRUG 10-[GAMMA-DIETHYLAMINOPROPYLAMINO]-6-METHYL-5H-PYRIDO[3',4'-4,5]PYRROLO[2,3-G]ISOQUINOLINE (BD-40), A PYRIDOPYRROLOISOQUINOLINE DERIVATIVE, TO INDUCE DNA STRAND BREAKS INVIVO AND ITS NONMUTAGENICITY IN YEAST
MOUSTACCHI, E
FAVAUDON, V
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CANCER RESEARCH, 1983, 43 (08) : 3700 - 3706
[30] PRODUCTION OF PROTEIN-ASSOCIATED DNA BREAKS BY 10-[DIETHYLAMINOPROPYLAMINO]-6-METHYL-H-5-PYRIDO[3',4'-4,5]PYRROLO[2,3-G]ISOQUINOLINE IN CULTURED L1210 CELLS AND IN ISOLATED-NUCLEI - COMPARISON WITH OTHER TOPOISOMERASE-II INHIBITORS
PIERSON, V
PIERRE, A
POMMIER, Y
GROS, P
CANCER RESEARCH, 1988, 48 (06) : 1404 - 1409

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