Sodium carbonate as a solid-phase reagent for the generation of acetylketene

被引：9
|
作者：
Bell, Kelcey [1 ]
Sadasivam, Dhandapani V. [1 ]
Gudipati, Indra Reddy [1 ]
Ji, Hua [1 ]
Birney, David [1 ]
机构：
[1] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79409 USA
来源：
TETRAHEDRON LETTERS | 2009年 / 50卷 / 12期
基金：
美国国家科学基金会;
关键词：
ASYMMETRIC CATALYSIS;
D O I：
10.1016/j.tetlet.2009.01.008
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Reaction of a toluene solution of 3-oxobutanoyl chloride (14) with Na2CO3 in the presence of a catalytic amount of triethylamine at 78 degrees C generates a solution of acetylketene (2), the dimer of which was isolated. Acetylketene (2) was trapped with 2-propanone, 2-propanol, and ethyl vinyl ether. (C) 2009 Elsevier Ltd. All rights reserved.
引用
收藏
页码：1295 / 1297
页数：3
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