The IIIb isoform of fibroblast growth factor receptor 2 is required for proper growth and branching of pancreatic ductal epithelium but not for differentiation of exocrine or endocrine cells

被引:0
|
作者
Huotari, M
Spencer-Dene, B
Palgi, J
Dickson, C
Otonkoski, T
机构
[1] Imperial Canc Res Fund, Viral Carcinogenesis Lab, London WC2A 3PX, England
[2] Univ Helsinki, Biomedicum Helsinki, Program Dev & Reprod Biol, Helsinki, Finland
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
68
引用
收藏
页码:A25 / A25
页数:1
相关论文
共 50 条
  • [21] Altered expression of fibroblast growth factor receptor 2 isoform IIIc: relevance to endometrioid adenocarcinoma carcinogenesis and histological differentiation
    Peng, Wei-Xia
    Kudo, Mitsuhiro
    Fujii, Takenori
    Teduka, Kiyoshi
    Naito, Zenya
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2014, 7 (03): : 1069 - 1076
  • [22] Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells
    Bae, Jae Hyun
    Boggon, Titus J.
    Tome, Francisco
    Mandiyan, Valsan
    Lax, Irit
    Schlessinger, Joseph
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (07) : 2866 - 2871
  • [23] Fibroblast growth factor receptor 2 IIIb invalidation - A potential cause of familial duodenal atresia
    Fairbanks, TJ
    Kanard, R
    Del Moral, PM
    Sala, FG
    De Langhe, S
    Warburton, D
    Anderson, KD
    Bellusci, S
    Burns, RC
    JOURNAL OF PEDIATRIC SURGERY, 2004, 39 (06) : 872 - 874
  • [24] An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis
    De Moerlooze, L
    Spencer-Dene, B
    Revest, JM
    Hajihosseini, M
    Rosewell, I
    Dickson, C
    DEVELOPMENT, 2000, 127 (03): : 483 - 492
  • [25] Reduced Expression of Fibroblast Growth Factor Receptor 2IIIb in Hepatocellular Carcinoma Induces a More Aggressive Growth
    Amann, Thomas
    Bataille, Frauke
    Spruss, Thilo
    Dettmer, Katja
    Wild, Peter
    Liedtke, Christian
    Muehlbauer, Marcus
    Kiefer, Paul
    Oefner, Peter J.
    Trautwein, Christian
    Bosserhoff, Anja-Katrin
    Hellerbrand, Claus
    AMERICAN JOURNAL OF PATHOLOGY, 2010, 176 (03): : 1433 - 1442
  • [26] Overexpression of fibroblast growth factor receptor 4 in high-grade pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma
    Motoda, Norio
    Matsuda, Yoko
    Onda, Munehiko
    Ishiwata, Toshiyuki
    Uchida, Eiji
    Naito, Zenya
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2011, 38 (01) : 133 - 143
  • [27] Celecoxib suppresses fibroblast growth factor-2 expression in pancreatic ductal adenocarcinoma PANC-1 cells
    Li, Jing
    Luo, Miaosha
    Wang, Yan
    Shang, Boxin
    Dong, Lei
    ONCOLOGY REPORTS, 2016, 36 (03) : 1345 - 1352
  • [28] Hepatocyte growth factor (HGF) induces differentiation of pancreatic ductal cells into insulin-producing cells
    Anastasi, E
    Bulotta, A
    Fallucca, S
    Perfetti, R
    Di Mario, U
    DIABETOLOGIA, 2001, 44 : A118 - A118
  • [29] The Significance of Fibroblast Growth Factor Receptor 2 Expression in Differentiation of Hepatocellular Carcinoma
    Harimoto, Norifumi
    Taguchi, Kenichi
    Shirabe, Ken
    Adachi, Eisuke
    Sakaguchi, Yoshihisa
    Toh, Yasushi
    Okamura, Takeshi
    Kayashima, Hiroto
    Taketomi, Akinobu
    Maehara, Yoshihiko
    ONCOLOGY, 2010, 78 (5-6) : 361 - 368
  • [30] Heparan Sulfate Domains Required for Fibroblast Growth Factor 1 and 2 Signaling through Fibroblast Growth Factor Receptor 1c
    Schultz, Victor
    Suflita, Mathew
    Liu, Xinyue
    Zhang, Xing
    Yu, Yanlei
    Li, Lingyun
    Green, Dixy E.
    Xu, Yongmei
    Zhang, Fuming
    DeAngelis, Paul L.
    Liu, Jian
    Linhardt, Robert J.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 292 (06) : 2495 - 2509