Reaction of nonstabilized azomethine ylides with Mannich bases: an approach to 3-acylpyrrolidines

被引：5

作者：

Gorbunova, Evgeniya V. ^{[1
]}

Buev, Evgeny M. ^{[1
]}

Moshkin, Vladimir S. ^{[1
]}

Sosnovskikh, Vyacheslav Ya. ^{[1
]}

机构：

[1] Ural Fed Univ, Inst Nat Sci & Math, Ekaterinburg 620000, Russia

来源：

MENDELEEV COMMUNICATIONS | 2019年 / 29卷 / 02期

基金：

俄罗斯科学基金会;

关键词：

CYCLOADDITION REACTIONS; PYRROLIDINES; POTENT;

D O I：

10.1016/j.mencom.2019.03.008

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Mannich bases obtained from cycloalkanones and methyl ketones decompose on heating to give alpha,beta-enones, which react in situ with nonstabilized azomethine ylides formed from spiro[anthracene-oxazolidines]. The final products, 3-acylpyrrolidines, were obtained in yields of 21-79% by heating the starting compounds in a microwave reactor in o-xylene at 210 degrees C for 45 min.

引用

页码：145 / 146

页数：2

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