Reaction of nonstabilized azomethine ylides with Mannich bases: an approach to 3-acylpyrrolidines

被引：5
|
作者：
Gorbunova, Evgeniya V. [1 ]
Buev, Evgeny M. [1 ]
Moshkin, Vladimir S. [1 ]
Sosnovskikh, Vyacheslav Ya. [1 ]
机构：
[1] Ural Fed Univ, Inst Nat Sci & Math, Ekaterinburg 620000, Russia
来源：
MENDELEEV COMMUNICATIONS | 2019年 / 29卷 / 02期
基金：
俄罗斯科学基金会;
关键词：
CYCLOADDITION REACTIONS; PYRROLIDINES; POTENT;
D O I：
10.1016/j.mencom.2019.03.008
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Mannich bases obtained from cycloalkanones and methyl ketones decompose on heating to give alpha,beta-enones, which react in situ with nonstabilized azomethine ylides formed from spiro[anthracene-oxazolidines]. The final products, 3-acylpyrrolidines, were obtained in yields of 21-79% by heating the starting compounds in a microwave reactor in o-xylene at 210 degrees C for 45 min.
引用
收藏
页码：145 / 146
页数：2
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