A clinical isolate of Escherichia coli co-harbouring mcr-1 and blaNDM-5 in Japan

被引:15
|
作者
Uchida, Hiroki [1 ]
Tada, Tatsuya [1 ]
Sugahara, Yoshie [2 ]
Kato, Akira [3 ]
Miyairi, Isao [4 ,5 ]
Kirikae, Teruo [1 ]
机构
[1] Juntendo Univ, Dept Microbiol, Sch Med, Bunkyo Ku, Tokyo 1138421, Japan
[2] Natl Ctr Child Hlth & Dev, Dept Nursing, Setagaya Ku, Tokyo 1578535, Japan
[3] Natl Ctr Child Hlth & Dev, Dept Clin Lab Med, Clin Microbiol Lab, Setagaya Ku, Tokyo 1578535, Japan
[4] Natl Child Hlth & Dev, Div Infect Dis, Dept Med Subspecialties, Setagaya Ku, Tokyo 1578535, Japan
[5] Univ Tennessee, Hlth Sci Ctr, Dept Microbiol Immunol & Biochem, Memphis, TN 38138 USA
基金
日本学术振兴会;
关键词
CRE; colistin resistance; Mcr-1; NDM-5; BETA-LACTAMASE; PLASMIDS;
D O I
10.1099/jmm.0.000793
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The mcr-1 gene encodes a phosphoethanolamine transferase, which confers resistance to colistin by transferring phosphoethanolamine to lipid A. This study describes the emergence of a colistin- and carbapenem-resistant clinical isolate of Escherichia coli harbouring mcr-1 and bla(NDM-5) genes, located on 90 and 150 Kb plasmids, respectively. The isolate belonged to ST132. This is the first report of a clinical isolate in Japan co-harbouring mcr-1 and bla(NDM-5).
引用
收藏
页码:1047 / 1049
页数:3
相关论文
共 50 条
  • [31] High Incidence of Escherichia coli Strains Coharboring mcr-1 and blaNDM from Chickens
    Liu, Bao-Tao
    Song, Feng-Jing
    Zou, Ming
    Zhang, Qi-Di
    Shan, Hu
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2017, 61 (03)
  • [32] Emergence of coexistence of a novel blaNDM-5-harbouring IncI1-I plasmid and an mcr-1.1-harbouring IncHI2 plasmid in a clinical Escherichia coli isolate in China
    Zhang, Xiaofan
    Chen, Lingxia
    Zhang, Xia
    Wang, Qian
    Quan, Jingjing
    He, Jintao
    Pan, Hongying
    Li, Xi
    [J]. JOURNAL OF INFECTION AND PUBLIC HEALTH, 2022, 15 (12) : 1363 - 1369
  • [33] Rapid emergence of high-level tigecycline resistance in Escherichia coli strains harbouring blaNDM-5 in vivo
    Li, Xi
    Mu, Xinli
    Yang, Yunxing
    Hua, Xiaoting
    Yang, Qing
    Wang, Nanfei
    Du, Xiaoxing
    Ruan, Zhi
    Shen, Xiaoqiang
    Yu, Yunsong
    [J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2016, 47 (04) : 324 - 327
  • [34] Characterization of the IncFII-IncFIB(pB171) Plasmid Carrying blaNDM-5 in Escherichia coli ST405 Clinical Isolate in Japan
    Takayama, Yoko
    Sekizuka, Tsuyoshi
    Matsui, Hidehito
    Adachi, Yuzuru
    Eda, Ryotaro
    Nihonyanagi, Shin
    Wada, Tatsuhiko
    Matsui, Mari
    Suzuki, Satowa
    Takaso, Masashi
    Kitasato, Hidero
    Kuroda, Makoto
    Hanaki, Hideaki
    [J]. INFECTION AND DRUG RESISTANCE, 2020, 13 : 561 - 566
  • [35] Emergence of Escherichia coli harbouring mcr-1 and mcr-3 genes in North West Algerian farmlands
    Touati, Meriem
    Hadjadj, Linda
    Berrazeg, Meryem
    Baron, Sophie Alexandra
    Rolain, Jean Marc
    [J]. JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE, 2020, 21 : 132 - 137
  • [36] Colistin- and Carbapenem-Resistant Escherichia coli Harboring mcr-1 and blaNDM-5, Causing a Complicated Urinary Tract Infection in a Patient from the United States
    Mediavilla, Jose R.
    Patrawalla, Amee
    Chen, Liang
    Chavda, Kalyan D.
    Mathema, Barun
    Vinnard, Christopher
    Dever, Lisa L.
    Kreiswirth, Barry N.
    [J]. MBIO, 2016, 7 (04):
  • [37] Research note: characteristics of blaNDM and mcr-1 co-producing Escherichia coli from retail chicken meat
    Zhao, Wenbo
    Wan, Shuigen
    Li, Shihong
    Li, Wenjun
    Kang, Jin
    Liu, Yong
    Huang, Hexiang
    Li, Hao
    Du, Xiang-Dang
    Xu, Chunyan
    Yao, Hong
    [J]. POULTRY SCIENCE, 2024, 103 (11)
  • [38] Coexistence of MCR-1 and NDM-9 in a clinical carbapenem-resistant Escherichia coli isolate
    Lai, Chih-Cheng
    Chuang, Yin-Ching
    Chen, Chi-Chung
    Tang, Hung-Jen
    [J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2017, 49 (04) : 517 - 518
  • [39] Coexistence of MCR-1 and NDM-9 in a clinical carbapenem-resistant Escherichia coli isolate
    Lai, Chih-Cheng
    Chen, Chi-Chung
    Chuang, Yin-Ching
    Tang, Hung-Jen
    [J]. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2017, 50 : S239 - S239
  • [40] Emergence of two Escherichia coli strains co-harboring mcr-1 and blaNDM in fresh vegetables from China
    Liu, Bao-Tao
    Song, Feng-Jing
    [J]. INFECTION AND DRUG RESISTANCE, 2019, 12 : 2627 - 2635