Novel synthesis and Bridgehead functionalization of permethylbicyclo[2.2.2]octasilane

被引：15

作者：

Setaka, W ^{[1
]}

Hamada, N ^{[1
]}

Kira, M ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Sci, Dept Chem, Aoba Ku, Sendai, Miyagi 9808578, Japan

来源：

CHEMISTRY LETTERS | 2004年 / 33卷 / 05期

关键词：

D O I：

10.1246/cl.2004.626

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Selective bridgehead chlorination of permethylbicyclo[2.2.2]octasilane 1 giving the corresponding 1-chloro- (2a) and 1,4-dichlorobicyclooctanes 3a was achieved using BCl3 in chloroform. 1-Chlorobicyclooctane 2a resists the reactions with various nucleophiles such as phenyllithium and lithium aluminum hydride but reacts with KC8 affording the corresponding silylpotasium 2b in quantitative yield.

引用

页码：626 / 627

页数：2

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