Solubility and degradation of paracetamol in subcritical water

被引:17
|
作者
Emire, Zuhal [1 ]
Yabalak, Erdal [1 ]
Goermez, Zkan [1 ]
Gizir, Ahmet Murat [1 ]
机构
[1] Mersin Univ, Fac Arts & Sci, Dept Chem, Ciftlikkoy Campus, TR-TR33343 Mersin, Turkey
关键词
subcritical water medium; approximation model; paracetamol; degradation; solubility; RESPONSE-SURFACE METHODOLOGY; ADVANCED OXIDATION PROCESSES; WASTE-WATER; DRINKING-WATER; PHARMACEUTICALS; REMOVAL; ACID; EXTRACTION; SAND; DECOMPOSITION;
D O I
10.2298/JSC160520079E
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
In this study, solubility and degradation of paracetamol were examined using subcritical water. The effect of temperature and static time was investigated during the solubility process in subcritical water at constant pressure (50 bar). The experimental results showed that temperature and static time have crucial effects on the degradation and solubility degrees. The maximal solubility of paracetamol was obtained at 403 K as (14.68 +/- 0.74) x 10(3). An approximation model for the solubility of paracetamol was proposed. O-2 and H2O2 were used for the degradation of paracetamol. The maximum degradation degree was found as 68.66 +/- 1.05 % and 100 +/- 0.00 % using O-2 and H2O2, respectively.
引用
收藏
页码:99 / 106
页数:8
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