CD74 Is Expressed in Relapsed and Refractory Multiple Myeloma and Can be Targeted with a Novel Anti-CD74 Antibody Drug Conjugate, STRO-001

被引：0
|
作者：
Embry, Millicent
Li, Xiaofan
Yu, Abigail
Abrahams, Cristina
Greenland, Nancy Y.
Wen, Kwun Wah
Jones, Chris
DeAlmeida, Venita
Krimm, Stellanie
Krueger, Sarah
Matheny, Shannon
Kline, Toni
Yam, Alice
Stafford, Ryan
Wiita, Arun P.
Hallam, Trevor
Lupher, Mark
Molina, Arturo
机构：
来源：
BLOOD | 2017年 / 130卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
4420
引用
收藏
页数：3
相关论文
共 50 条
  • [21] CD74 Expression by AML Cell Lines and Bone Marrow Specimens, and Augmented In Vitro Cytotoxicity of Anti-CD74 Antibody After Interferon-Gamma (IFN-γ) Treatment
    Chandra, Abhinav B.
    Burton, Jack
    Stein, Rhona
    Chen, Susan
    Mishra, Nidhi
    Shah, Taral
    Enwemnwa, Nneamaka N.
    Goldenberg, David
    BLOOD, 2010, 116 (21) : 1190 - 1190
  • [22] Cure of SCID mice bearing human B-lymphoma xenografts by an Anti-CD74 antibody-anthracycline drug conjugate
    Griffiths, GL
    Mattes, MJ
    Stein, R
    Govindan, SV
    Horak, ID
    Hansen, HJ
    Goldenberg, DM
    CLINICAL CANCER RESEARCH, 2003, 9 (17) : 6567 - 6571
  • [23] The combination of milatuzumab, a humanized anti-CD74 antibody, and veltuzumab, a humanized anti-CD20 antibody, demonstrates activity in patients with relapsed and refractory B-cell non-Hodgkin lymphoma
    Christian, Beth A.
    Poi, Ming
    Jones, Jeffrey A.
    Porcu, Pierluigi
    Maddocks, Kami
    Flynn, Joseph M.
    Benson, Don M.
    Phelps, Mitch A.
    Wei, Lai
    Byrd, John C.
    Wegener, William A.
    Goldenberg, David M.
    Baiocchi, Robert A.
    Blum, Kristie A.
    BRITISH JOURNAL OF HAEMATOLOGY, 2015, 169 (05) : 701 - 710
  • [24] Cellular association and cytotoxicity of doxorubicin-loaded immunoliposomes targeted via Fab' fragments of an anti-CD74 antibody
    Lundberg, B. B.
    Griffiths, G.
    Hansen, H. J.
    DRUG DELIVERY, 2007, 14 (03) : 171 - 175
  • [25] Single Cell RNA-Seq Analysis Revealed MIF/CD74 Pathway Determinants of BCMA CART Resistance in Relapsed/Refractory Multiple Myeloma
    Chen, Xinzhuo
    Huang, Renhua
    Wang, Huiping
    Xiao, Hao
    Li, Qian
    Zhai, Zhimin
    Wang, Zhitao
    BLOOD, 2024, 144 : 4764 - 4765
  • [26] Improved therapy of multiple myeloma by combining milatuzumab (Anti-CD74 humanized mAb) and bortezomib: In vitro and in vivo results
    Stein, Rhona
    Goldenberg, David M.
    BLOOD, 2007, 110 (11) : 356A - 357A
  • [27] A Phase I Study of Milatuzumab, a Humanized Anti-CD74 Antibody, and Veltuzumab, a Humanized Anti-CD20 Antibody, In Patients with Relapsed and Refractory B-Cell Non-Hodgkin's Lymphoma
    Christian, Beth
    Alinari, Lapo
    Earl, Christian Tyler
    Wilding, Emily
    Quinion, Carl
    Lustberg, Mark
    Benson, Don M., Jr.
    Jones, Jeffrey A.
    Byrd, John C.
    Wegener, William A.
    Goldenberg, David M.
    Baiocchi, Robert A.
    Blum, Kristie A.
    BLOOD, 2010, 116 (21) : 1148 - 1149
  • [28] SGN-CD352A: A novel humanized anti-CD352 antibody -drug conjugate for the treatment of multiple myeloma
    Lewis, Tim
    Olson, Devra J.
    Gordon, Kristine A.
    Sandal, Sharsti L.
    Miyamoto, Jamie
    VVestendorf, Lori
    Linares, Germein
    Leiske, Chris
    Kostner, Heather
    Stone, Ivan
    Anderson, Martha
    Nesterova, Albina
    Jonas, Mechthild
    Law, Che-Leung
    CANCER RESEARCH, 2016, 76
  • [29] Results of A Phase 1 Study of Milatuzumab, a Humanized Anti-CD74 Antibody, and Veltuzumab, a Humanized Anti-CD20 Antibody, In Patients with Relapsed and Refractory B-Cell Non-Hodgkin's Lymphoma
    Christian, Beth
    Alinari, Lapo
    Jones, Jeffrey A.
    Benson, Don M., Jr.
    Flynn, Joseph M.
    Porcu, Pierluigi
    Lustberg, Mark E.
    Phelps, Mitchell
    Poi, Ming
    Chung, Diana
    Quinion, Carl
    Byrd, John C.
    Wegener, William
    Goldenberg, David M.
    Baiocchi, Robert A.
    Blum, Kristie A.
    BLOOD, 2011, 118 (21) : 1584 - 1584
  • [30] Cure of athymic mice given lethal injections of Raji lymphoma cells by a single dose of an anti-CD74 antibody-anthracycline drug conjugate.
    Griffiths, GL
    Mattes, MJ
    Stein, R
    Von Govindan, S
    Horak, ID
    Hansen, HJ
    Goldenberg, DM
    CLINICAL CANCER RESEARCH, 2003, 9 (16) : 6187S - 6187S
12345