The complementary roles of the extrinsic and intrinsic apoptotic pathways in promoting the death of cancer cells

被引:2
|
作者
Mayes, Patrick A.
El-Deiry, Wafik S.
机构
[1] Univ Penn, Sch Med, Lab Mol Oncol & Cell Cycle Regulat, Dept Med Hematol Oncol, Philadelphia, PA 19104 USA
[2] Univ Penn, Sch Med, Dept Genet, Philadelphia, PA 19104 USA
[3] Univ Penn, Sch Med, Dept Pharmacol, Inst Translat Med & Therapeut, Philadelphia, PA 19104 USA
[4] Univ Penn, Sch Med, Abramson Comprehens Canc Ctr, Philadelphia, PA 19104 USA
来源
CANCER JOURNAL | 2006年 / 12卷 / 04期
关键词
TRAIL; apoptosis; cancer; p53; caspase; intrinsic pathway; extrinsic pathway; chemotherapy; combination therapy;
D O I
10.1097/00130404-200607000-00001
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:247 / 249
页数:3
相关论文
共 50 条
  • [21] Sesamol induced apoptotic effect in lung adenocarcinoma cells through both intrinsic and extrinsic pathways
    Siriwarin, Boondaree
    Weerapreeyakul, Natthida
    CHEMICO-BIOLOGICAL INTERACTIONS, 2016, 254 : 109 - 116
  • [22] Palmitic acid-induced cell death in NGF differentiated PC12 cells activates the extrinsic and intrinsic apoptotic pathways
    Almaguel, F
    Liu, J
    De Leon, M
    JOURNAL OF NEUROCHEMISTRY, 2004, 90 : 9 - 9
  • [23] Activation of intrinsic and extrinsic pathways in apoptotic signaling during UV-C-induced death of Jurkat cells: the role of caspase inhibition
    Scoltock, AB
    Cidlowski, JA
    EXPERIMENTAL CELL RESEARCH, 2004, 297 (01) : 212 - 223
  • [24] Gambogic acid sensitizes breast cancer cells to TRAIL-induced apoptosis by promoting the crosstalk of extrinsic and intrinsic apoptotic signalings
    Wang, Shengpeng
    Xu, Yingqi
    Li, Chenyang
    Tao, Hongxun
    Wang, Anqi
    Sun, Chenyu
    Zhong, Zhangfeng
    Wu, Xu
    Li, Peng
    Wang, Yitao
    FOOD AND CHEMICAL TOXICOLOGY, 2018, 119 : 334 - 341
  • [25] Anticancer activity of a cyclooxygenase inhibitor, CX9051, in human prostate cancer cells: the roles of NF-κB and crosstalk between the extrinsic and intrinsic apoptotic pathways
    Chiung-Hua Huang
    Jih-Hwa Guh
    Grace Shiahuy Chen
    Pin-Hsuan Lu
    Ji-Wang Chern
    Naunyn-Schmiedeberg's Archives of Pharmacology, 2010, 382 : 159 - 169
  • [26] Anticancer activity of a cyclooxygenase inhibitor, CX9051, in human prostate cancer cells: the roles of NF-κB and crosstalk between the extrinsic and intrinsic apoptotic pathways
    Huang, Chiung-Hua
    Guh, Jih-Hwa
    Chen, Grace Shiahuy
    Lu, Pin-Hsuan
    Chern, Ji-Wang
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 2010, 382 (02) : 159 - 169
  • [27] Bacteria induced extrinsic and intrinsic apoptotic pathways in the rat gastrointestinal system
    Mete, Ergun
    Cevahir, Nural
    Oguz, Emin Oguzhan
    Sahin, Barbaros
    Kaleli, Ilknur
    Ozdemir, Mehmet B.
    Koseler, Aylin
    Mete, Gulcin Abban
    BIOMEDICAL RESEARCH-INDIA, 2017, 28 (04): : 1670 - 1676
  • [28] Shear stress promotes anoikis resistance of cancer cells via caveolin-1-dependent extrinsic and intrinsic apoptotic pathways
    Li, Shun
    Chen, Yu
    Zhang, Yuehui
    Jiang, Xiaomin
    Jiang, Ying
    Qin, Xiang
    Yang, Hong
    Wu, Chunhui
    Liu, Yiyao
    JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 234 (04) : 3730 - 3743
  • [29] The extrinsic and intrinsic apoptotic pathways are involved in manganese toxicity in rat astrocytoma C6 cells
    Alaimo, Agustina
    Gorojod, Roxana M.
    Kotler, Monica L.
    NEUROCHEMISTRY INTERNATIONAL, 2011, 59 (02) : 297 - 308
  • [30] A novel copper (II) complex activated both extrinsic and intrinsic apoptotic pathways in liver cancerous cells
    Rezaei, Azadeh
    Mahmoodi, Mehdi
    Mohammadizadeh, Fatemeh
    Mohamadi, Maryam
    Hajizadeh, Mohammad Reza
    Mirzaei, Mohammad Reza
    Falahati-pour, Soudeh Khanamani
    JOURNAL OF CELLULAR BIOCHEMISTRY, 2019, 120 (08) : 12280 - 12289