A new simple visible spectrophotometric method is developed for the estimation of clarithromycin in pure and pharmaceutical dosage forms. The method is based on, the reaction of the drug with marquis reagent which forms a brown coloured chromogen with absorption maximum at 495 am. The chromogen formed is stable and obeys Beer's law in the concentration range of 10-70 mug/mL.
机构:
Natl Inst Pharmaceut Res & Dev, Dept Med Chem & Qual Control, Abuja, NigeriaNatl Inst Pharmaceut Res & Dev, Dept Med Chem & Qual Control, Abuja, Nigeria
Afieroho, O. E.
Okorie, O.
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Univ Port Harcourt, Fac Pharmaceut Sci, Pharmaceut & Pharmaceut Technol Dept, Port Harcourt, NigeriaNatl Inst Pharmaceut Res & Dev, Dept Med Chem & Qual Control, Abuja, Nigeria
Okorie, O.
Okonkwo, T. J. N.
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Univ Port Harcourt, Fac Pharmaceut Sci, Dept Pharmaceut & Med Chem, Port Harcourt, NigeriaNatl Inst Pharmaceut Res & Dev, Dept Med Chem & Qual Control, Abuja, Nigeria
机构:
Department of Medicinal Chemistry,Faculty of Pharmacy and Drug Design and Development Research Center,Tehran University of Medical SciencesDepartment of Medicinal Chemistry,Faculty of Pharmacy and Drug Design and Development Research Center,Tehran University of Medical Sciences