The small molecule axl inhibitor BGB324 shows activity against T315I-mutated and BCR-ABL1 wt chronic myeloid leukemia

被引:0
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作者
Erdmann, R. [1 ,2 ]
Jorgensen, H. [3 ]
Ben-Batalla, I. [1 ,2 ]
Kruse, N. [1 ,2 ]
Micklem, D. [4 ]
von Amsberg, G. [1 ]
Schafhausen, P. [1 ]
Schultze, A. [1 ]
Wroblewski, M. [1 ,2 ]
Binder, M. [1 ]
Cubas-Cordova, M. [1 ,2 ]
Hadlich, T. [1 ]
Janing, M. [1 ,2 ]
Sawall, S. [1 ,2 ]
Witzke, V. [1 ,2 ]
Lorens, J. [4 ]
Allan, E. [3 ]
Mukherjee, L. [3 ]
Morrison, H. [3 ]
Cassells, J. [3 ]
Koerger, N. [5 ]
Lorens, J. B. [6 ]
Clark, R. [7 ]
Koschmieder, S. [8 ]
Vandenberghe, P. [9 ]
Bruemmendorf, T. [8 ]
Hochhaus, A. [10 ]
Carmeliet, P. [11 ]
Holyoake, T. [3 ]
Pantel, K. [2 ]
Bokemeyer, C. [1 ,12 ]
Loges, S. [1 ,2 ]
机构
[1] Univ Med Ctr Hamburg Eppendorf, Med Clin 2, Hamburg, Germany
[2] Dept Tumor Biol, Hamburg, Germany
[3] Univ Glasgow, Paul OGorman Leukemia Res Ctr, Coll Med Vet & Life Sci, Glasgow, Lanark, Scotland
[4] BerGenBio AS, Jonas Lies, Bergen, Norway
[5] Univ Med Ctr Hamburg Eppendorf, Ctr Oncol, Bone Marrow Transplantat Unit, Hamburg, Germany
[6] Univ Bergen, Dept Biomed, Bergen, Norway
[7] Univ Liverpool, Royal Liverpool Univ Hosp, Liverpool L69 3BX, Merseyside, England
[8] Univ Klinikum RWTH Aachen, Aachen, Germany
[9] Katholieke Univ Leuven, Ctr Human Genet, Leuven, Belgium
[10] Univ Klinikum Jena, Klin Innere Med 2, Jena, Germany
[11] VIB, Lab Angiogenesis & Neurovasc Link, Vesalius Res Ctr, Leuven, Belgium
[12] Univ Med Ctr Eppendorf, Hubertus Wald Univ Canc Ctr, Dept Hematol & Oncol, Hamburg, Germany
关键词
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中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
V935
引用
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页码:309 / 309
页数:1
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