Unrelated allogeneic bone marrow transplant in adrenoleukodystrophy using CD34+ stem cell selection

被引：4

作者：

Borker, A ^{[1
]}

Yu, LC ^{[1
]}

机构：

[1] Louisiana State Univ, Hlth Sci Ctr, Childrens Hosp New Orleans, Dept Pediat Hematol Oncol, New Orleans, LA 70118 USA

来源：

METABOLIC BRAIN DISEASE | 2002年 / 17卷 / 03期

关键词：

adrenoleukodystrophy; allogeneic BMT; CD34(+) selection;

D O I：

10.1023/A:1019969820308

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Adrenoleukodystrophy is an inherited disease characterized by progressive neurodegeneration with rapid deterioration to a vegetative state. Of the treatment modalities tried to date, BMT is the only one with the potential for cure. However, the high rate of morbidity and mortality associated with allogeneic transplant makes it necessary to try out novel measures to improve the outcome in these patients. We report here a case where we used CD34(+) stem cell selection for allogeneic unrelated-donor BMT in a patient with adrenoleukodystrophy.

引用

页码：139 / 142

页数：4

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