The Treatment of Inflammatory Bowel Disease in Patients With a History of Malignancy

被引：19
|
作者：
Lin, Steven C. [1 ]
Goldowsky, Alex [2 ]
Papamichael, Konstantinos [1 ]
Cheifetz, Adam S. [1 ]
机构：
[1] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Ctr Inflammatory Bowel Dis, Div Gastroenterol, Boston, MA 02115 USA
[2] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Dept Med, Boston, MA 02115 USA
来源：
INFLAMMATORY BOWEL DISEASES | 2019年 / 25卷 / 06期
关键词：
cancer; adverse events; lymphoma; melanoma; nonmelanoma; biologic therapy; immunomodulators; NONMELANOMA SKIN-CANCER; NECROSIS-FACTOR ANTAGONISTS; LONG-TERM SAFETY; INCREASED RISK; RHEUMATOID-ARTHRITIS; CROHNS-DISEASE; COLORECTAL-CANCER; MAINTENANCE THERAPY; RECEIVE THIOPURINES; ULCERATIVE-COLITIS;
D O I：
10.1093/ibd/izy376
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
As patients with inflammatory bowel disease (IBD) are living longer and our medical armamentarium expands, gastroenterologists are more frequently faced with treatment decisions about patients with IBD who also have a history of malignancy. This review aims to summarize the current literature on IBD, the inherent risk of developing gastrointestinal and extra-intestinal malignancies, and the risk of malignancies associated with available biologic and immunomodulatory therapies and to discuss the overall treatment strategy for a patient with a history of malignancy.
引用
收藏
页码：998 / 1005
页数：8
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