De-palmitoylation of Cysteine 202 of Cyclophilin-D by Calcium is Important for the Activation of the Permeability Transition Pore

被引:0
|
作者
Amanakis, Georgios [1 ]
Sun, Junhui [2 ]
Fergusson, Maria [1 ]
Liu, Chengyu [1 ]
Molkentin, Jeff D. [3 ]
Murphy, Elizabeth [4 ]
机构
[1] NIH, Bldg 10, Bethesda, MD 20892 USA
[2] NHLBI, NIH, Bldg 10, Bethesda, MD 20892 USA
[3] Childrens Hosp, Med Ctr, Cincinnati, OH 45229 USA
[4] NHLBI, Bldg 10, Bethesda, MD 20892 USA
关键词
D O I
10.1161/res.127.suppl_1.MP124
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
AMP124
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Cyclophilin D palmitoylation and permeability transition: a new twist in the tale of myocardial ischaemia-reperfusion injury
    Main, Alice
    Robertson-Gray, Olivia
    Fuller, William
    CARDIOVASCULAR RESEARCH, 2021, 117 (01) : 15 - 17
  • [32] Increased expression and intramitochondrial translocation of cyclophilin-D associates with increased vulnerability of the permeability transition pore to stress-induced opening during compensated ventricular hypertrophy
    Matas, Jimmy
    Young, Nicholas Tien Sing
    Bourcier-Lucas, Celine
    Ascah, Alexis
    Marcil, Mariannick
    Deschepper, Christian F.
    Burelle, Yan
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2009, 46 (03) : 420 - 430
  • [33] Activation of Cyclophilin D Induces the Initial Process of Kidney Stone Formation Via Mitochondrial Permeability Transition Pore Opening
    Niimi, K.
    Yasui, T.
    Hirose, Y.
    Hamamoto, S.
    Kobayashi, T.
    Hirose, M.
    Okada, A.
    Itoh, Y.
    Tozawa, K.
    Kohri, K.
    UROLOGY, 2012, 80 (03) : S315 - S315
  • [34] Implication of Cyclophilin D and Permeability Transition Pore in Mitochondrial Vulnerability of Compensated Heart Hypertrophy
    Matas, Jimmy
    Ascah, Alexis
    Marcil, Mariannick
    Deschepper, Christian
    Burelle, Yan
    FASEB JOURNAL, 2008, 22
  • [35] Phosphate is essential for inhibition of the mitochondrial permeability transition pore by cyclosporin A and by cyclophilin D ablation
    Basso, Emy
    Petronilli, Valeria
    Forte, Michael A.
    Bernardi, Paolo
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2008, 283 (39) : 26307 - 26311
  • [36] Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition
    Woodfield, K
    Rück, A
    Brdiczka, D
    Halestrap, AP
    BIOCHEMICAL JOURNAL, 1998, 336 : 287 - 290
  • [37] Mitochondrial permeability transition pore in Alzheimer's disease: Cyclophilin D and amyloid beta
    Du, Heng
    Yan, Shirley ShiDu
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2010, 1802 (01): : 198 - 204
  • [38] Muscle denervation promotes opening of the permeability transition pore and increases the expression of cyclophilin D
    Csukly, Kristina
    Ascah, Alexis
    Matas, Jimmy
    Gardiner, Phillip F.
    Fontaine, Eric
    Burelle, Yan
    JOURNAL OF PHYSIOLOGY-LONDON, 2006, 574 (01): : 319 - 327
  • [39] Structural mechanisms of cyclophilin D-dependent control of the mitochondrial permeability transition pore
    Gutierrez-Aguilar, Manuel
    Baines, Christopher P.
    BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 2015, 1850 (10): : 2041 - 2047
  • [40] Direct demonstration of a specific interaction between cyclophilin-D and the adenine nucleotide translocase confirms their role in the mitochondrial permeability transition
    Woodfield, K.
    Ruck, A.
    Brdiczka, D.
    Halestrap, A.P.
    Biochemical Journal, 1998, 336 (pt 2): : 287 - 290