Polyphenols in Stachys and Betonica species (Lamiaceae)

Above-ground parts and roots from four Stachys species (S. germanica L., S. sylvatica L. and the Balkan endemics S. thracica Dav. and S. plumosa Griseb.) as well as of three Betonica species (B. officinalis L. and the Balkan endemics B. bulgarica Deg. et Neic. and B scardica Griseb.) were screened for phenols (phenylethanoid glycosides, flavonoid glycosides and the phenolic diterpene betolide). Three phenylethanoid glycosides, a flavonoid glycoside and the phenolic diterpene betolide were isolated and identified, most of them for the first time in the investigated species. The results obtained support the view that Stachys and Betonica are well separated genera.