Oral factor Xa inhibitors in acute coronary syndromes

被引：1

作者：

Tapp, Luke ^{[1
]}

Wrigley, Ben ^{[1
]}

Lip, Gregory Y. H. ^{[1
]}

机构：

[1] Univ Birmingham, Haemostasis Thrombosis & Vasc Biol Unit, Ctr Cardiovasc Sci, City Hosp, Birmingham B18 7QH, W Midlands, England

来源：

NATURE REVIEWS CARDIOLOGY | 2009年 / 6卷 / 10期

关键词：

DEEP-VEIN THROMBOSIS; RIVAROXABAN; TRIAL; CLOPIDOGREL; APIXABAN; ASPIRIN; SAFETY;

D O I：

10.1038/nrcardio.2009.160

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Factor Xa inhibitors, a new class of oral anticoagulants, have been evaluated in the phase II ATLAS ACS-TIMI 46 and APPRAISE trials. addition of these agents to standard therapy has tended to reduce the incidence of adverse cardiovascular events at the expense of a dose-dependent increase in the risk of bleeding complications.

引用

页码：619 / 620

页数：3

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