Application of microextraction techniques in alternative biological matrices with focus on forensic toxicology: a review

被引：9
|
作者：
Brandao da Costa, Bruno Ruiz [1 ]
Ramos Santos Junior, Wilson Jose [1 ]
Maximiano, Isabela Fernanda [2 ]
Gomes, Nayna Candida [1 ]
Freitas, Bruno Toledo [2 ]
De Martinis, Bruno Spinosa [2 ]
机构：
[1] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Ave Cafe S-N, BR-14040903 Ribeirao Preto, SP, Brazil
[2] Univ Sao Paulo, Fac Filosofia Ciencias & Letras Ribeirao Preto, Av Bandeirantes 3900, BR-14040900 Ribeirao Preto, Brazil
来源：
BIOANALYSIS | 2021年 / 13卷 / 01期
关键词：
alternative samples; drugs of abuse; green chemistry; microextraction; sample preparation; SOLID-PHASE MICROEXTRACTION; LIQUID-LIQUID MICROEXTRACTION; CHROMATOGRAPHY-MASS-SPECTROMETRY; GAS-CHROMATOGRAPHY; PACKED SORBENT; ORAL FLUID; ELECTROMEMBRANE EXTRACTION; HAIR SAMPLES; HUMAN SALIVA; PSYCHOACTIVE SUBSTANCES;
D O I：
10.4155/bio-2020-0241
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The interest in alternative biological matrices (e.g., hair and saliva) for forensic toxicology analysis has increased, and recent developments in sample preparation have targeted rapid, cheap, efficient and eco-friendly methods, including microextraction techniques. For this review, we have gathered information about these two hot topics. We discuss the composition, incorporation of analytes and advantages and disadvantages of different biological matrices, and also present the operation principles of the most reported microextraction procedures and their application in forensic toxicology. The outcome of this review may encourage future forensic researches into alternative samples and microextraction techniques.
引用
收藏
页码：45 / 64
页数：20
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