Patient-derived tumor microenvironment models uncover non-autonomous TKI resistance mechanisms in NSCLC

被引:0
|
作者
Hu, Haichuan
Niederst, Matthew
Engelman, Jeffrey
机构
关键词
D O I
10.1158/1538-7445.AM2016-299
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
299
引用
收藏
页数:2
相关论文
共 50 条
  • [31] Development of a multicellular pancreatic tumor microenvironment system using patient-derived tumor cells
    Gioeli, Daniel
    Snow, Chelsi J.
    Simmers, Michael B.
    Hoang, Stephen A.
    Figler, Robert A.
    Allende, J. Ashe
    Roller, Devin G.
    Parsons, J. Thomas
    Wulfkuhle, Julia D.
    Petricoin, Emanuel F.
    Bauer, Todd W.
    Wamhoff, Brian R.
    LAB ON A CHIP, 2019, 19 (07) : 1193 - 1204
  • [32] Dostarlimab shows dose-dependent immune activation of the tumor microenvironment in a patient-derived NSCLC explant model similar to pembrolizumab
    Perrin, Jessica
    Wippich, Frank
    Sherina, Valeriia
    Dvornikov, Dmytro
    Lupar, Katharina
    Melhem, Murad M.
    Hanafin, Patrick
    Waight, Jeremy
    Yu, Jong
    Yadavilli, Sapna
    Poeckel, Daniel
    Bergamini, Giovanna
    CANCER RESEARCH, 2023, 83 (07)
  • [33] DCE-MRI of patient-derived xenograft models of uterine cervix carcinoma: associations with parameters of the tumor microenvironment
    Anette Hauge
    Catherine S. Wegner
    Jon-Vidar Gaustad
    Trude G. Simonsen
    Lise Mari K. Andersen
    Einar K. Rofstad
    Journal of Translational Medicine, 15
  • [34] Patient-derived lymphoma spheroids integrating immune tumor microenvironment as preclinical follicular lymphoma models for personalized medicine
    Faria, Carla
    Gava, Fabien
    Gravelle, Pauline
    Valero, Juan Garcia
    Dobano-Lopez, Celia
    Van Acker, Nathalie
    Quelen, Cathy
    Jalowicki, Gael
    Morin, Renaud
    Rossi, Cedric
    Lagarde, Jean-Michel
    Fournie, Jean-Jacques
    Ysebaert, Loic
    Laurent, Camille
    Perez-Galan, Patricia
    Bezombes, Christine
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2023, 11 (10)
  • [35] Integration of Tumor Microenvironment in Patient-Derived Organoid Models Help Define Precision Medicine of Renal Cell Carcinoma
    Wang, Bingran
    Xue, Yizheng
    Zhai, Wei
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [36] In vivo and in vitro generation and characterization of EGFR TKI resistance in a patient-derived and a cell line-derived xenograft model of NSCLC with activating EGFR mutations.
    McKenzie, Andrew J.
    Cranston, Aaron N.
    Papadopouloul, Nektaria
    Jiang, Simon
    Wrigley, Jane
    Yin, Yinfei
    Li, Henry
    Page, Martin
    Kumari, Rajendra
    MOLECULAR CANCER THERAPEUTICS, 2013, 12 (11)
  • [37] DCE-MRI of patient-derived xenograft models of uterine cervix carcinoma: associations with parameters of the tumor microenvironment
    Hauge, Anette
    Wegner, Catherine S.
    Gaustad, Jon-Vidar
    Simonsen, Trude G.
    Andersen, Lise Mari K.
    Rofstad, Einar K.
    JOURNAL OF TRANSLATIONAL MEDICINE, 2017, 15
  • [38] MET activation and Cetuximab resistance in patient-derived tumor xenografts
    Krumbach, Rebekka
    Schuler, Julia
    Hofmann, Michael
    Fiebig, Heinz-Herbert
    Beckers, Thomas
    MOLECULAR CANCER THERAPEUTICS, 2009, 8 (12)
  • [39] A Patient-Derived Xenograft Model of Human Lymphomas Which Preserves the Tumor Microenvironment
    Burack, R.
    Spence, S.
    Bankert, R. B.
    Bernstein, S.
    LABORATORY INVESTIGATION, 2014, 94 : 340A - 340A
  • [40] Identification of tumor microenvironment components in patient-derived pancreatic ductal adenocarcinoma organoids
    Gao, Mei
    Bailey, Charles J.
    Harper, Megan M.
    Cavnar, Michael J.
    Pandalai, Prakash
    Qasem, Shadi A.
    Kim, Joseph
    CANCER RESEARCH, 2022, 82 (10)