The prognosis of women with acute myocardial infarction is poor as more than twice as many women than men will die within 6 months after myocardial infarction (25,8% vs. 10%). This detrimental prognosis is caused by differences in the epidemiological characteristics of women with an acute myocardial infarction. these women are about 10 years older arrive later in the emergency department and receive less often thrombolytic therapy than men. Although thrombolytic therapy improves significantly the prognosis of women, this treatment is often withheld due to the risk of cerebral bleeding in women. If the risk of cerebral bleeding is estimated to be exceedingly high (age > 65 years, severe hypertension, low body weight t-PA thrombolysis) acute balloon, angioplasty is an effective alternative to treat women with acute myocardial infarction and improve prognosis.