FlyBase: updates to the Drosophila melanogaster knowledge base

被引:275
|
作者
Larkin, Aoife [1 ]
Marygold, Steven J. [1 ]
Antonazzol, Giulia [1 ]
Attrill, Helen [1 ]
dos Santos, Gilberto [2 ]
Garapati, Phani, V [1 ]
Goodman, Joshua L. [3 ]
Gramates, L. Sian [2 ]
Millburn, Gillian [1 ]
Strelets, Victor B. [3 ]
Tabone, Christopher J. [2 ]
Thurmond, Jim [3 ]
机构
[1] Univ Cambridge, Dept Physiol Dev & Neurosci, Downing St, Cambridge CB2 3DY, England
[2] Harvard Univ, Biol Labs, 16 Divin Ave, Cambridge, MA 02138 USA
[3] Indiana Univ, Dept Biol, Bloomington, IN 47405 USA
基金
美国国家卫生研究院; 英国医学研究理事会;
关键词
FLYATLAS;
D O I
10.1093/nar/gkaa1026
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
FlyBase (flybase.org) is an essential online database for researchers using Drosophila melanogaster as a model organism, facilitating access to a diverse array of information that includes genetic, molecular, genomic and reagent resources. Here, we describe the introduction of several new features at FlyBase, including Pathway Reports, paralog information, disease models based on orthology, customizable tables within reports and overview displays ('ribbons') of expression and disease data. We also describe a variety of recent important updates, including incorporation of a developmental proteome, upgrades to the GAL4 search tab, additional Experimental Tool Reports, migration to JBrowse for genome browsing and improvements to batch queries/downloads and the Fast-Track Your Paper tool.
引用
收藏
页码:D899 / D907
页数:9
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