Studies on the binding of tris(1,10-phenanthroline) nickel(II) to calf thymus DNA

被引：0
|
作者：
Jin, L
Yang, P
Li, QS
Yang, BS
机构：
[1] NANJING UNIV, STATE KEY LAB COORDINAT CHEM, NANJING 210093, PEOPLES R CHINA
[2] SHANXI UNIV, INST MOL SCI, TAIYUAN 030006, JAPAN
来源：
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES | 1997年 / 13卷 / 03期
关键词：
chiral metal complexes; DNA; binding mode;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Absorbance and fluorescence methods were used to study the interaction of Delta- and Lambda-tris(phenanthroline) nickel(II) complex with calf thymus DNA. It was concluded that Delta-Ni(phen)(3)(2+) preferentially bound to DNA. Especially the fluorescence Scatchard plots were discussed for the binding of EthBr to calf thymus DNA in the presence of varying concentrations of the metal complex. Theses studies indicated that both the isomers bound to DNA by two acting types, namely, intercalative and electrostatic bound modes.
引用
收藏
页码：201 / 206
页数：6
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