Smart stimuli-responsive drug delivery systems based on cyclodextrin: A review

被引：155

作者：

Tian, Bingren ^{[1
]}

Liu, Yumei ^{[1
]}

Liu, Jiayue ^{[2
]}

机构：

[1] Xinjiang Univ, Coll Chem & Chem Engn, Urumqi 830001, Peoples R China

[2] Ningxia Med Univ, Sch Pharm, Yinchuan 750004, Ningxia, Peoples R China

来源：

CARBOHYDRATE POLYMERS | 2021年 / 251卷

基金：

中国国家自然科学基金;

关键词：

Stimuli-response; Cyclodextrin; Drug delivery system; Clinic application; Precise treatment; MESOPOROUS SILICA NANOPARTICLES; GRAFTED BETA-CYCLODEXTRIN; PRECISION MEDICINE; CONTROLLED-RELEASE; REDOX; POLYMER; PH; NANOTECHNOLOGY; NANOCARRIER; ASSEMBLIES;

D O I：

10.1016/j.carbpol.2020.116871

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Stimulated by researches in materials chemistry and medicine fields, drug delivery has entered a new stage of development. Drug delivery systems have been extensively studied according to the differences in the drug therapeutic environment such as pH, light, temperature, magnet, redox, enzymes, etc. Cyclodextrin is a smart tool that has been proven to be used in the preparation of drug delivery, and has become a new area of concern in recent years. In this review, we discuss recent research advances in smart stimuli-responsive cyclodextrin-based drug delivery. First, different stimuli-responsive drug delivery systems based on cyclodextrin are introduced and classified. Then, the characteristics of different types of stimuli-responsive drug delivery systems are described, and their applications are emphasized. Finally, current challenges and future development opportunities of smart stimuli-responsive drug delivery systems based on cyclodextrin are discussed.

引用

页数：14

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