Histochemical localization of alcohol dehydrogenase activities in the livers of mice, rats, hamsters, and guinea-pigs

被引：4
|
作者：
Watabiki, T
Tokiyasu, T
Yoshida, M
Okii, Y
Yoshimura, S
Akane, A
机构：
[1] Department of Legal Medicine, Kansai Medical University, Moriguchi
[2] Department of Legal Medicine, Kansai Medical University, Moriguchi, Osaka 570
来源：
ACTA HISTOCHEMICA ET CYTOCHEMICA | 1997年 / 30卷 / 04期
关键词：
alcohol dehydrogenase; histochemistry; alcohol preference; liver; rodents;
D O I：
10.1267/ahc.30.381
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The hepatic lobular localization of alcohol dehydrogenase (ADH) activity was examined histochemically in mice, rats, hamsters and guinea-pigs with the nitro blue tetrazolium method. In the mouse liver, the ADH activity was localized mainly in the centrilobular zone. In the rat and hamster livers, it was observed throughout the lobule, with increased centrilobular staining. Interestingly, in the guinea-pig liver, if was found to be evenly localized in both the centrilobular and periportal zones, with little or no midlobular staining. These findings show that the distribution pattern of ADH activity in the hepatic lobule of the guinea-pigs differs strikingly from that of the mice, rats and hamsters.
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页码：381 / 387
页数：7
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